中风与神经疾病杂志2025，Vol.42Issue(5)：409-413,5.DOI:10.19845/j.cnki.zfysjjbzz.2025.0078
散发性成人杆状体肌病的研究进展
Research advances in sporadic late-onset nemaline myopathy
摘要
Abstract
Sporadic late-onset nemaline myopathy(SLONM)is a rare,acquired,and treatable myopathy with a sub-acute or chronic progressive clinical course,characterized by asymmetric muscle atrophy and weakness in the axial and limb muscles,with or without involvement of respiratory and cardiac muscles.The only definitive diagnostic method at present is the identification of rods accumulation in muscle fibers by muscle biopsy pathology.This article provides a re-view of the clinical manifestations,diagnostic evaluations,muscle pathology,and advances in the treatment of SLONM.关键词
散发性成人杆状体肌病/肌肉病理/M蛋白/自体干细胞移植/免疫治疗Key words
Sporadic late-onset nemaline myopathy/Muscle pathology/M protein/Autologous stem cell transplantation/Immunotherapy分类
医药卫生引用本文复制引用
赵冰,焉传祝..散发性成人杆状体肌病的研究进展[J].中风与神经疾病杂志,2025,42(5):409-413,5.基金项目
国家自然科学基金面上项目(82071412) （82071412）
青岛市自然科学基金青年项目(24-4-4zrjj-104-jch) （24-4-4zrjj-104-jch）
青岛市神经系统罕见病临床医学研究中心(22-3-7-lczx-3-nsh) （22-3-7-lczx-3-nsh）
