中国感染控制杂志2025，Vol.24Issue(5)：682-686,5.DOI:10.12138/j.issn.1671-9638.20257013
长沙市48例猴痘患者临床与流行病学特征
Clinical and epidemiological characteristics of 48 monkeypox patients in Changsha City
摘要
Abstract
Objective To analyze the clinical data of 48 monkeypox patients in Changsha City,improve the under-standing and early diagnosis on monkeypox,and provide scientific basis for the prevention and control of monkeypox outbreak.Methods Clinical data of 48 monkeypox patients admitted to The First Hospital of Changsha City from June 29,2023 to September 30,2024 were collected retrospectively.Epidemiological data,clinical manifestations,diagnosis,and treatment process of patients were analyzed.Results All of the 48 patients were male,with a medi-an age of 33 years old(19-54 years old).95.83％(n=46)of the patients were men who had sex with men(MSM),and 93.75％(n=45)admitted to having sex with men prior to disease onset.Patients primarily presented with fever(43.75％)and rash(97.92％)as clinical manifestations,62.50％(n=30)of the patients had concurrent human immunodeficiency virus(HIV)infection,and those with HIV infection had more severe skin rashes.After symp-tomatic and supportive treatment,most patients had good prognoses,but two HIV-infected patients died.Conclusion MSM are high-risk population for this monkeypox outbreak,and close contact is the main route of transmission.Patients present with fever and rash as major clinical manifestations.Monkeypox patients with con-current HIV infection have more severe skin rashes.Most monkeypox patients have good prognoses,HIV co-infec-tion and low CD4+T lymphocyte counts may be high-risk factors for death.Epidemic prevention and control should be carried out among high-risk population,and suspected rashes should be detected and treated as early as possible.关键词
猴痘/猴痘病毒/临床特征/流行病学特征Key words
monkeypox/monkeypoxvirus/clinical characteristics/epidemiological characteristics分类
医药卫生引用本文复制引用
刘纯,王宁..长沙市48例猴痘患者临床与流行病学特征[J].中国感染控制杂志,2025,24(5):682-686,5.基金项目
长沙市自然科学基金项目(kp22022012) （kp22022012）
