中国老年保健医学2025，Vol.23Issue(2)：128-131,4.DOI:10.3969/j.issn.1672-2671.2025.02.025
代谢综合征合并脑小血管病相关睡眠障碍的研究进展
Research progress on sleep disorders related to metabolic syndrome combined with cerebrovascular disease
摘要
Abstract
The incidence of metabolic syndrome(MS),cerebrovascular disease(CSVD)and sleep disorder,often occur together,Previous studies were mostly limited to the direction of a single disease.With the deepening of the study,it was found that the inci-dence rate of sleep disorders in MS patients with CSVD was significantly increased,and the risks of MS and CSVD in patients with sleep disorders were also significantly increased.The three are closely related and the pathogenesis is partially overlapping.This arti-cle summarizes the common mechanisms of MS,CSVD,and sleep disorders,and analyzes the causes of sleep disorders.The common mechanism between MS and CSVD involves insulin resistance,fatty acid metabolism disorders,oxidative stress,and chronic inflam-mation.The common mechanisms of MS and sleep disorders involve insulin resistance,obesity,oxidative stress,and metabolic disor-ders.The circulatory mechanism of CSVD and sleep disorders involves neurological dysfunction,chronic cerebral ischemia,and hy-poperfusion.The impact of MS on sleep disorders can be divided into respiratory and non respiratory problems,with respiratory prob-lems mainly being obstructive sleep apnea hypopnea syndrome.The impact of CSVD on sleep disorders is mainly related to brain tis-sue damage caused by cerebral hypoperfusion and fluid regulation factors.Through comprehensive analysis,the above three factors are each other's risk factors,which can accelerate their respective development processes and ultimately form a vicious cycle.Early as-sessment and timely intervention can help break this vicious cycle.关键词
代谢综合征/脑小血管病/睡眠障碍Key words
metabolic syndrome/cerebrovascular disease/sleep disorders引用本文复制引用
周汝君,郑梅红,李燕清,叶玲,黄敏学,尹莲花..代谢综合征合并脑小血管病相关睡眠障碍的研究进展[J].中国老年保健医学,2025,23(2):128-131,4.基金项目
国家自然科学基金青年科学基金项目(编号:82004441),福建省教育厅引导性项目(编号:2024Y0016) （编号:82004441）
