中国医院用药评价与分析2025，Vol.25Issue(5)：524-529,6.DOI:10.14009/j.issn.1672-2124.2025.05.003
三化汤的历史沿革与现代临床应用分析
Historical Evolution and Modern Clinical Application of Sanhua Decoction
摘要
Abstract
OBJECTIVE:To systematically analyze the ancient and modern literature on the classic prescription of Sanhua decoction,and to examine the key information and modern application of Sanhua decoction,with a view to providing scientific basis for its clinical development and application.METHODS:The ancient and modern literature of Sanhua decoction was retrieved,and metrological methods were used to authenticate the information on the prescription source,composition,dosage,concoctions,preparation and serving methods,and main treatment of diseases,as well as to analyze the modern clinical application of Sanhua decoction.RESULTS:A total of 174 pieces of ancient literature information were collected,which involved 95 ancient Chinese medical books,of which 35(4 Jin-Yuan,17 Ming,14 Qing)ancient Chinese medical books recorded the composition,concoctions and dosages in detail.The composition of Sanhua decoction was mainly Magnolia officinalis,Radix et rhizoma rhei,Fructus aurantii immaturus,and Radix et rhizoma notopterygii.Magnolia officinalis was selected as ginger Magnolia officinalis,Radix et rhizoma rhei was selected as wine Radix et rhizoma rhei,Fructus aurantii immaturus,and Radix et rhizoma notopterygii were raw products.According to the ancient dosage conversion,it was recommended that Magnolia officinalis,Radix et rhizoma rhei,Fructus aurantii immaturus,and Radix et rhizoma notopterygii were 9.3 g,and the dosage was adjusted according to the urgency of the patients'condition and age.If it was to be taken throughout the day with the degree of slight benefits,it was recommended that the ratio of drug dosage to added water should be 1∶23,and the dosage should be halved.If it was to be taken for the whole day with slight benefit,it was recommended that the ratio of drug dosage to added water should be 1∶15,and the dosage should be halved.The indications recorded in ancient books were stoke,with six meridians in the exterior and the obstruction of defecation in the interior.Modern clinical treatment was mainly used for stroke,post-stroke constipation,cerebral hemorrhage or cerebrovascular disease,and the efficacy of ancient records was basically the same.CONCLUSIONS:With reference to the requirements of Principles of Examination of Key Information of Ancient Classical Formulas,the information of Sanhua decoction such as the source of prescription,composition,dosage,concoction,method of preparation and method of serving,and main treatment of diseases are examined,and combined with the modern clinical research,to provide reference for the application of material basis of Sanhua decoction compound preparation.关键词
经典名方/三化汤/历史沿革/现代临床应用Key words
Classical prescription/Sanhua decoction/Historical evolution/Modern clinical application分类
药学引用本文复制引用
赵静霞,贡磊磊,冯欣..三化汤的历史沿革与现代临床应用分析[J].中国医院用药评价与分析,2025,25(5):524-529,6.基金项目
国家自然科学基金青年科学基金项目(No.82204698) （No.82204698）
北京市属医院科研培育计划项目(No.PZ2023029) （No.PZ2023029）
