中国医院用药评价与分析2025，Vol.25Issue(5)：530-535,6.DOI:10.14009/j.issn.1672-2124.2025.05.004
中医药治疗干眼的临床证据图谱研究
Clinical Evidence Mapping Research of Traditional Chinese Medicine Intervention in the Treatment of Dry Eye
摘要
Abstract
OBJECTIVE:To explore and present the quality of evidence for traditional Chinese medicine in the treatment of dry eye through the analysis of evidence from the relevant literature in systematic review/Meta-analysis of traditional Chinese medicine in the treatment of dry eye.METHODS:CNKI,VIP,Wanfang Data,SinoMed,PubMed,Web of Science,Embase,and the Cochrane Library databases were retrieved to collect systematic review/Meta-analysis of traditional Chinese medicine in the treatment of dry eye from the establishment of the database to May 15th,2024.The methodological quality assessment tool of systematic review/Meta-analysis(AMSTAR2 scale)was used to evaluate the methodological quality of the included literature,and the evidence map was used to present the measures of traditional Chinese medicine in the treatment of dry eye,amount of included literature,research conclusions,and methodological quality assessment results.RESULTS:Finally,41 articles were included,and acupuncture accounted for a large proportion of the treatment measures,followed by integrated traditional Chinese and Western medicine.According to the evaluation results of the AMSTAR2 scale,the elaboration results of previous research protocol design and revision details,the basis of study design,the list of excluded literature with the rationale,the information on the funding of the fund for the inclusion of literature,and the potential conflict of interest were poor.The evidence map showed that traditional Chinese medicine had significant therapeutic effect on dry eye,among which acupuncture treatment was more effective than other methods.Among all the included literature,38 articles clearly put forward the conclusion that it was beneficial,and 3 articles suggested that it might be beneficial.CONCLUSIONS:The overall quality of evidence in traditional Chinese medicine in the treatment of dry eye is low,suggesting that more high-quality clinical large-sample and large-cohort studies should be actively carried out in the future to provide evidence-based evidence,improve the rigor and scientificalness of clinical research.关键词
中医药/干眼/证据图谱Key words
Traditional Chinese medicine/Dry eye/Evidence map分类
药学引用本文复制引用
张致睿,刘长兴,刘悦,姚靖..中医药治疗干眼的临床证据图谱研究[J].中国医院用药评价与分析,2025,25(5):530-535,6.基金项目
国家自然科学基金资助项目(No.81973908) （No.81973908）
黑龙江省中医药管理局项目(No.ZYW2022-051) （No.ZYW2022-051）
