中国医学装备2025，Vol.22Issue(5)：6-9,15,5.DOI:10.3969/j.issn.1672-8270.2025.05.002
微波消融治疗甲状腺微小乳头状癌术后吸收效果的影响因素分析
Analysis on influencing factors of postoperative absorption effect of microwave ablation for papillary thyroid microcarcinoma
摘要
Abstract
Objective:To explore the influencing factors of absorption effect postoperative ablation area after microwave ablation(MWA)for papillary thyroid microcarcinoma(PTMC).Methods:The clinical and ultrasound data of 101 patients with single PTMC who underwent microwave ablation in Beijing Friendship Hospital between April 2019 and July 2023 were collected.According to the endpoint event of whether the ablation area disappeared one year after MWA,they were divided into disappearance group(52 cases)and non-disappearance group(49 cases).Univariate and multivariate logistic regression were used to analyze the factors of affecting the absorption effect of ablation area,and a regression model was constructed.Receiver operating characteristic(ROC)curve was drawn to test the predictive efficacy of the model.Results:There were significant differences in the age,coarse calcification in the nodule,ablation time,Hashimoto's thyroiditis between two groups(x2=4.708,12.180,19.497,8.457,P<0.05),respectively.There were also significant differences in maximum diameter of nodule,nodule volume,ablation energy between two groups(Z=-3.929,-3.969,-3.677,P<0.05).Multivariate logistic regression analysis showed that age≥50 years old,coarse calcification in the nodule,ablation time≥50s,and Hashimoto's thyroiditis were independent influencing factors for the non-disappearance of ablation area one year after MWA for PTMC(OR=4.464,3.733,10.063,4.173,P<0.05).The ROC curve analysis showed that the area under curve(AUC)of the regression model in predicting non-disappearance of ablation area after MWA for PTMC was 0.853(95%CI:0.777-0.929),and the diagnostic sensitivity and specificity of that were respectively 75.5%and 82.7%.Conclusion:The logistic regression model,that is constructed on the basis of clinical information,preoperative ultrasound features,and thermal ablation parameters,has high clinical application value in predicting the postoperative absorption of the ablation area in patients who undergo MWA for PTMC.关键词
甲状腺微小乳头状癌(PTMC)/微波消融/影响因素/超声特征Key words
Papillary thyroid microcarcinoma(PTMC)/Microwave ablation(MWA)/Influencing factor/Ultrasonography features分类
医药卫生引用本文复制引用
曹欣然,郭瑞芳,杨沛沛,钱林学..微波消融治疗甲状腺微小乳头状癌术后吸收效果的影响因素分析[J].中国医学装备,2025,22(5):6-9,15,5.基金项目
首都卫生发展科研专项(首发2022-1-2022) Capital's Funds for Health Improvement and Research(2022-1-2022) （首发2022-1-2022）
