中国中医药信息杂志2025，Vol.32Issue(6)：45-51,7.DOI:10.19879/j.cnki.1005-5304.202411682
基于症状-证候-药物的新安医家治疗肝硬化数据挖掘研究
Data Mining Study on Xin'an Doctors for the Treatment of Liver Cirrhosis Based on Symptoms-Syndromes-Medicines
摘要
Abstract
Objective To explore the characteristics of Xin'an doctors in the syndrome differentiation and treatment of liver cirrhosis from the dimensions of symptoms,syndromes and medication using data mining methods.Methods Medical cases and prescriptions for liver cirrhosis were collected from Xin'an medical literature.Data mining was performed using frequency analysis,complex network analysis,Louvain clustering analysis and factor analysis to investigate syndromes,symptoms,and medicines.Results A total of 363 prescriptions were analyzed,involving 15 syndromes and 325 kinds of Chinese materia medica,with 33 identified as core medications.Tonifying herbs were the most frequently used;the primary syndromes were liver qi stagnation and water retention;core symptoms of liver qi stagnation included emotional distress,reduced appetite and hypochondriac pain,with core medications such as Bupleuri Radix and Poria;core symptoms of water retention included lower limb edema and abdominal distension,with core medications such as Pinelliae Rhizoma,Citri Reticulatae Pericarpium,Magnoliae Officinalis Cortex and Poria.Factor analysis of core medications identified 12 common factors.Conclusion The pathogenesis of liver cirrhosis involves deficiency in nature and excess in superficiality,primarily affecting the liver and closely related to the spleen and kidneys.Xin'an doctors emphasize treating the symptoms with qi-regulating,blood-activating,dampness-drying and heat-clearing strategies,while simultaneously addressing the root with qi-tonifying,spleen-strengthening,liver-nourishing and kidney-replenishing therapies.关键词
肝硬化/新安医学/证候/症状/用药/数据挖掘Key words
liver cirrhosis/Xin'an medicine/syndromes/symptoms/medication/data mining分类
医药卫生引用本文复制引用
王慧,郑荟元,冯景熙,李玟,胡继礼,吴鹏..基于症状-证候-药物的新安医家治疗肝硬化数据挖掘研究[J].中国中医药信息杂志,2025,32(6):45-51,7.基金项目
国家自然科学基金(82074385) （82074385）
安徽省自然科学基金(1908085MH266) （1908085MH266）
