中成药2025，Vol.47Issue(5)：1539-1547,9.DOI:10.3969/j.issn.1001-1528.2025.05.019
刺茶美登木茎枝化学成分研究
Chemical constituents from the stems and barks of Maytenus variabilis
摘要
Abstract
AIM To study the chemical constituents from the stems and barks of Maytenus variabilis(Hemsl.)C.Y.Cheng.METHODS The 95％ethanol extract from the stems and barks of M.variabilis was isolated and purified by silica gel,Sephadex LH-20 and semi preparative HPLC,then the structures of obtained compounds were identified by physicochemical properties and spectral data.RESULTS Twenty-three compounds were isolated and identified as β-amyrin(1),3β-acetoxyolean-12-en-11-one(2),ursa-12-ene-11-one-3-ol octocosate(3),friedelin(4),canophyllol(5),pinoresinol(6),medioresinol(7),isolariciresinol(8),dihydrodehydrodiconiferyl alcohol(9),vanillic acid(10),7R,8S-5-methoxydihydrodehydroconiferyl alcohol(11),β-hydroxypropiovanillone(12),triptregeline B(13),triptregeline E(14),(+)-evofolin B(15),2,5-dimethoxybenzoquinone(16),olean-12-ene-3,11-dione(17),β-sitosterol(18),(-)-(7R,7'R,7"S,8S,8'S,8"S)-4',4"-dihydroxy-3,3',3",5-tetramethoxy-7,9',7',9-diepoxy-4,8"-oxy-8,8'-sesquineolignan-7",9"-diol(19),phyllostadimer B(20),rayalinol(21),lyoniresinol(22),dihydrobuddlenol B(23).CONCLUSION Compounds 3,9-11,13-14,16,19-21,23 are isolated from genus Maytenus for the first time,and compounds 2,4-5,7-8,12,15,17,22 are first found from this plant.关键词
刺茶美登木/茎枝/化学成分/分离鉴定Key words
Maytenus variabilis(Hemsl.)C.Y.Cheng/stems and barks/chemical constituents/isolation and identification分类
医药卫生引用本文复制引用
何婷,刘冰倩,陈剑锋,尉小琴,刘呈雄,邹坤,程凡..刺茶美登木茎枝化学成分研究[J].中成药,2025,47(5):1539-1547,9.基金项目
国家自然科学基金(82204237) （82204237）
