中国中医药信息杂志2025，Vol.32Issue(6)：193-196,后插1,5.DOI:10.19879/j.cnki.1005-5304.202410465
中药调控γ-氨基丁酸治疗焦虑症研究进展
Research Progress in Chinese Materia Medica Regulating GABA for the Treatment of Anxiety Disorders
摘要
Abstract
Anxiety disorder is a common emotional disorder,with its pathological mechanisms involving the imbalance of multiple neurotransmitter systems,especially the dysfunction of the gamma-aminobutyric acid(GABA)system.This article explored the TCM understanding of anxiety disorder,and summarized and organized the research on the regulation of GABA system in the treatment of anxiety disorders through TCM monomers and formulas from the aspects of terpenes,flavonoids,phenolic acids,lignans,cinnamic acids,saponins,etc.At present,the research mainly involved chrysin,baicalin,ginsenoside,Baihe Dihuang Decoction,Bentun Decoction,Suanzaoren Decoction,Chaihu Jia Longgu Muli Decoction,etc.The mechanism involved regulating the inflammatory response of the body,alleviating oxidative stress damage,restoring the hyperactive HPA axis and other action pathways,which could provide a reference for the related research of TCM anti anxiety treatment and the development of new drugs.关键词
中药单体/中药复方/焦虑症/γ-氨基丁酸/综述Key words
TCM monomers/compound prescriptions/anxiety disorder/gamma-aminobutyric acid/review分类
医药卫生引用本文复制引用
郭海鹏,王婷婷,邹蔓姝,赵洪庆,王宇红..中药调控γ-氨基丁酸治疗焦虑症研究进展[J].中国中医药信息杂志,2025,32(6):193-196,后插1,5.基金项目
国家自然科学基金(82174357) （82174357）
湖南省中医药管理局科研课题(B2023141) （B2023141）
湖南省自然科学基金(2023JJ60476) （2023JJ60476）
湖南中医药大学学科建设"揭榜挂帅"项目(22JBZ06) （22JBZ06）
湖南中医药大学研究生创新课题(2023CX126) （2023CX126）
