中国现代医生2025，Vol.63Issue(13)：1-4,9,5.DOI:10.3969/j.issn.1673-9701.2025.13.001
DCE-MRI定量参数与结直肠癌术前T分期相关性分析
Correlation analysis between DCE-MRI quantitative parameters and preoperative T staging of colorectal carcinoma
摘要
Abstract
Objective To analyze the correlation between quantitative parameters of dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI)and preoperative T staging of colorectal carcinoma(CRC).Methods The clinical data of 95 CRC patients admitted to the Second Affiliated Hospital of Nanchang University from May 2023 to July 2024 were retrospectively collected.All patients underwent DCE-MRI examination,and the quantitative parameters of DCE-MRI[rate constant(Kep),extravascular extracellular interstitial volume ratio(Ve),volume transfer constant(Ktrans),time to peak(TTP),maximum slope,maximum concentration]in patients with different T stages were compared.Kendall's tau-b correlation coefficient examined the relationship between DCE-MRI quantitative parameters and preoperative T staging of CRC,and receiver operating characteristic(ROC)curve was drawn to analyze the value of DCE-MRI quantitative parameters in the preoperative T3-4 stage of CRC patients.Results 95 CRC patients revealed 16 cases in T1 stage,32 cases in T2 stage,37 cases in T3 stage,and 10 cases in T4 stage.There were statistically significant differences in tumor diameter,Kep,Ve and Ktrans among CRC patients with different T stages(P＜0.05),and their sizes were T4＞T3＞T2＞T1.There were no significant differences in TTP,maximum slope and maximum concentration among CRC patients with different T stages(P＞0.05).Kendall's tau-b correlation coefficient test showed that Kep,Ve,Ktrans of DCE-MRI were positively correlated with preoperative T staging of CRC(P＜0.05).ROC curve results showed that area under the curve of Kep,Ve and Ktrans alone and in combination were all greater than 0.70 in the preoperative T3-4 stage of CRC patients,which had evaluation value,and the combined detection had the highest evaluation value.Conclusion The quantitative parameters of DCE-MRI are related to preoperative T staging of CRC and can evaluate the risk of T3-4 stage.关键词
结直肠癌/动态对比增强磁共振成像/T分期/相关性Key words
Colorectal carcinoma/Dynamic contrast-enhanced magnetic resonance imaging/T staging/Correlation分类
临床医学引用本文复制引用
熊小丽,后文涛,邓军..DCE-MRI定量参数与结直肠癌术前T分期相关性分析[J].中国现代医生,2025,63(13):1-4,9,5.基金项目
江西省卫生健康委科技计划项目(202310498) （202310498）
