中国现代医生2025，Vol.63Issue(13)：41-45,5.DOI:10.3969/j.issn.1673-9701.2025.13.010
宫颈活检LSIL患者转归的影响因素分析
Analysis of influencing factors on outcomes of LSIL patients undergoing cervical biopsy
路惠萍 1石岩玉 1王涵 1延怡迪 1周君羿 1赵书君1
作者信息
- 1. 郑州大学第三附属医院妇瘤科,河南郑州 450052
- 折叠
摘要
Abstract
Objective To investigate the factors influencing the natural outcome of low-grade squamous intraepithelial lesions(LSIL)of the cervix.Methods A total of 154 patients who underwent colposcopic cervical biopsy in the Third Affiliated Hospital of Zhengzhou University from January 2022 to January 2023 were selected and divided into negative conversion group(55 cases),continuous group(70 cases)and upgraded group(29 cases)according to the follow-up results.Logistic regression was used to analyze the influence of related factors on the outcome of LSIL.Results There were statistically significant differences in the number of vaginal births,the results of thin-prep cytology test,human papilloma virus(HPV)typing,whether vaginal LSIL was combined,whether there were symptoms,and vaginal microecology among three groups(P＜0.05).Multivariate Logistic analysis showed that combined vaginal LSIL,vaginal microecological abnormalities,atypical squamous cell-cannot exclude high-grade squamous intraepithelial lesion(ASC-H)/high-grade squamous intraepithelial lesion(HSIL),HPV 16/18 positive or mixed positive were independent risk factors for persistent infection(P＜0.05),combined vaginal LSIL,symptomatic,vaginal microecological abnormalities,ASC-H/HSIL,HPV 16/18 positive or mixed positive were all independent risk factors for escalation of lesions(P＜0.05).Conclusion Patients with vaginal LSIL,vaginal microecological abnormalities,ASC-H/HSIL,HPV 16/18 positive or mixed positive should be followed up and early intervention to reduce the risk of disease escalation.关键词
低级别鳞状上皮内病变/人乳头瘤病毒/预后/危险因素Key words
Low-grade squamous intraepithelial lesion/Human papilloma virus/Prognosis/Risk factor分类
临床医学引用本文复制引用
路惠萍,石岩玉,王涵,延怡迪,周君羿,赵书君..宫颈活检LSIL患者转归的影响因素分析[J].中国现代医生,2025,63(13):41-45,5.
