肿瘤防治研究2025，Vol.52Issue(5)：355-360,6.DOI:10.3971/j.issn.1000-8578.2025.24.1253
肿瘤免疫治疗与脂质代谢异常
Cancer Immunotherapy and Abnormal Lipid Metabolism
摘要
Abstract
Lipid metabolism relates to tumor proliferation,progression,and immune escape.With the rapid development of immunotherapy,the relationship between immunotherapy and lipid metabolism has been constantly explored.On the one hand,immunotherapy can cause dyslipidemia and accelerate the progression of atherosclerosis,which has been neglected by clinicians.On the other hand,lipid metabolism can affect antitumor immunity at multiple levels and potentially influence the efficacy of immunotherapy.Lipid metabolism-regulating drugs also have the potential to synergize with immunotherapy.This review summarizes relevant research evidence to inspire further exploration.关键词
免疫治疗/免疫检查点抑制剂/血脂异常Key words
Immunotherapy/Immune checkpoint inhibitors/Dyslipidemia分类
临床医学引用本文复制引用
姜文鑫,刘鹏..肿瘤免疫治疗与脂质代谢异常[J].肿瘤防治研究,2025,52(5):355-360,6.基金项目
Chinese Society of Clinical Oncology-BMS Immune-Oncology Research Fund(No.YBMS2019-026) 中国临床肿瘤协会—百时美施贵宝肿瘤免疫治疗研究基金(YBMS2019-026) （No.YBMS2019-026）
