中南民族大学学报（自然科学版）2025，Vol.44Issue(5)：593-600,8.DOI:10.20056/j.cnki.ZNMDZK.20240748
鬼箭锦鸡儿化学成分研究
Study on chemical constituents of Caragana jubata(pall.)Poir.
摘要
Abstract
The aerial parts and roots of Caragana jubata(Pall.)Poir.were extracted and purified,and nineteen compounds were isolated from the 75%ethanol extract of Caragana jubata and identified as erycibenin D(1),quercetin 3-O-β-D-glucopyranoside(2),kushenol I(3),(3R)-4′-methoxy-2′,3,7-trihydroxyisoflavanone(4),texasin(5),6,7,2′-trihydroxy-4′-methoxyisoflavone(6),daidzein(7),tectorigenin(8),(+)-5-methoxy-isolariciresinol(9),(6a R,11a R)-3,4-dihydroxy-9-methoxypterocarpan(10),(6a R,11a R)-3,8-dihydroxy-9-methoxypterocarpan(11),lespedezol D1(12),formononetin(13),7,3′-dihydroxyl-5′-methoxyisoflavone(14),liquiritigenin(15),calycosin(16),kaempferol 3-O-β-D-glucoside(17),kaempferol(18)and pterocarpin(19).Compounds 1-11 were isolated from this plant for the first time.The effects of the isolated compounds on the glucose uptake activity of rat skeletal muscle myoblasts(L6 cells)in vitro were evaluated.The results showed that compounds 1-3,5-7,9-12,14,16 and 19 could improve the glucose uptake ability of L6 cells to a certain extent,and the uptake activity increased by 0.35-1.92 folds.Among them,compound 3 exhibited the strongest activity among all the isolated compounds.It increased the glucose uptake activity by 1.92 folds at a concentration of 20 µg·mL-1.关键词
鬼箭锦鸡儿/化学成分/异黄酮/葡萄糖摄取Key words
Caragana jubata/chemical composition/isoflavone/glucose uptake分类
中医学引用本文复制引用
宋萍,亢诗雯,刘文琪,杨新洲..鬼箭锦鸡儿化学成分研究[J].中南民族大学学报（自然科学版）,2025,44(5):593-600,8.基金项目
青海省基础研究计划项目(2023-ZJ-922M) （2023-ZJ-922M）
