中南民族大学学报（自然科学版）2025，Vol.44Issue(5)：608-615,8.DOI:10.20056/j.cnki.ZNMDZK.20250505
金钌纳米颗粒修饰碳纤维电极用于多巴胺的检测
Au-Ru nanoparticle-modified carbon fibre microelectrode for the detection of dopamine
摘要
Abstract
Gold nanoparticles(AuNPs)and ruthenium nanoparticles(RuNPs)were synthesized using sodium citrate reduction method.They were then modified onto the surface of carbon fiber electrode(CFME)using electrochemical deposition method to construct a highly sensitive electrochemical sensor,AuNPs/RuNPs/CFME,for the quantitative detection of dopamine(DA).The morphology and structure of the materials and electrode were characterized using scanning electron microscopy,transmission electron microscopy,and ultraviolet spectrophotometry.The electrochemical behavior of DA on the modified electrode before and after modification was investigated using differential pulse voltammetry,cyclic voltammetry,and electrochemical impedance spectroscopy.The experimental results showed that the bimetallic nanoparticles exhibited a specific synergistic catalytic effect towards DA.The oxidation peak current of DA measured by DPV showed a good linear relationship with its concentration in the range of 0.1～10 µmol/L,with a detection limit(LOD)of 0.024 µmol/L(S/N=3).AuNPs/RuNPs/CFME demonstrated high stability and anti-interference ability.The analysis of DA in actual mouse serum samples using the spiked recovery method showed a recovery rate of 95%～105%and a relative standard deviation(RSD)of 1.82%～2.78%.关键词
多巴胺/碳纤维微电极/纳米钌/纳米金Key words
dopamine/carbon fiber microelectrode/ruthenium nanoparticles(RuNPs)/gold nanoparticles(AuNPs)分类
药学引用本文复制引用
潘彦冰,UCHKUN Ishimov,马雯雯,方涛,黄先菊,程寒..金钌纳米颗粒修饰碳纤维电极用于多巴胺的检测[J].中南民族大学学报（自然科学版）,2025,44(5):608-615,8.基金项目
湖北省科技攻关项目(2024EHA054) （2024EHA054）
湖北省国际科技合作基地(SH2311) （SH2311）
中南民族大学学术创新团队经费资助项目(XTZ24025) （XTZ24025）
