中华中医药学刊2025,Vol.43Issue(5):7-14,8.DOI:10.13193/j.issn.1673-7717.2025.05.002
氧化应激在多囊卵巢综合征中的作用机理及中医药治疗研究进展
Role of Oxidative Stress in Polycystic Ovary Syndrome and Traditional Chinese Medicine Treatment:A Review
摘要
Abstract
Polycystic ovary syndrome(PCOS)is an important cause of female infertility worldwide.It is characterized by hy-perandrogenism(HA),insulin resistance(IR),obesity,ovulation disorder and infertility,often accompanied by metabolic syn-drome and chronic low-grade inflammation,which seriously affects women's physical and mental health.The disease is affected by a variety of factors,and its etiology and pathogenesis are not clear.Oxidative stress(OS)refers to the imbalance between the oxidative system and antioxidant system in the human body.Studies have found that OS is closely related to the occurrence and development of PCOS,and can drive other pathological mechanisms to promote the development of PCOS,such as mitochondrial dysfunction and inflammatory response.This article summarized the correlation between OS and the main clinical symptoms of P-COS,and summed up the traditional Chinese medicine monomer,traditional Chinese medicine compound,Chinese patent medi-cine,acupuncture and moxibustion to reduce the status of OS in patients and improve the clinical symptoms of PCOS patients,in order to expand the application range of traditional Chinese medicine in the treatment of PCOS and provide reliable scientific theo-retical basis.关键词
多囊卵巢综合征/氧化应激/代谢异常/生殖健康/中医药治疗Key words
polycystic ovary syndrome/oxidative stress/metabolic disturbance/reproductive health/traditional Chinese medi-cine therapy分类
医药卫生引用本文复制引用
梁瑞宁,王雅凡,刘城移..氧化应激在多囊卵巢综合征中的作用机理及中医药治疗研究进展[J].中华中医药学刊,2025,43(5):7-14,8.基金项目
江西省重点研发计划"揭榜挂帅"项目(20223BBG71012) (20223BBG71012)
江西省教育厅科技研究项目(GJJ2200919) (GJJ2200919)
江西省中医药管理局科技项目(2021A155) (2021A155)
江西中医药大学校级科技创新团队发展计划项目(CXTD22013) (CXTD22013)