北京中医药大学学报2025，Vol.48Issue(5)：664-668,5.DOI:10.3969/j.issn.1006-2157.2025.05.010
基于"肾虚毒瘀"理论探讨通精解毒方在弱精子症中的应用
Application of Tongjing Jiedu Formula in the treatment of asthenospermia based on the"kidney deficiency toxic-stasis"theory
摘要
Abstract
Asthenospermia is one of the important causes of male infertility,and its etiology and pathogenesis are complex.Traditional Chinese medicine(TCM)offers unique advantages in treating this disease.The"kidney deficiency and toxic-stasis"theory reveals the dynamic relationship between kidney essence deficiency and the interaction of toxic-stasis in disease pathogenesis,which can be applied clinically to guide the differentiation and treatment of asthenospermia.The formation of asthenospermia is closely related to the deficiency of kidney essence and the blockage of toxic stasis.The kidney essence is the source of reproductive essence.If the kidney essence is depleted for a long time and the kidney essence is deficient,the essence chamber cannot be enriched,resulting in spermatozoa dysfunction and poor spermatozoa mobility.The poison stasis interferes with the spermatozoa and turns into spermatotoxin,which directly harms spermatozoa fertility and leads to the decrease of spermatozoa mobility.Tongjing Jiedu Formula takes tonifying kidney to supply essence,diuresis and detoxification,activating blood circulation and removing blood stasis as the treatment principle,focusing on tonifying kidney to fill essence and nourishing healthy qi to restore the nourishing effect of kidney essence,and also emphasizes clearing heat and detoxification,activating blood circulation and removing blood stasis,promoting diuresis and dredging collaterals to remove poisonous damp-heat and static blood and harmonize blood and vessel,improving spermatogenic environment and improving sperm vitality to help men have children.This article analyzes the application of Tongjing Jiedu Formula in treating asthenospermia from the perspective of"kidney deficiency and toxic stasis",aiming to provid new ideas and methods for the explanation of the pathogenesis of the disease and TCM treatment.关键词
肾虚毒瘀/通精解毒方/弱精子症/毒邪Key words
kidney deficiency and toxic stasis/Tongjing Jiedu Formula/asthenospermia/toxic pathogen分类
中医学引用本文复制引用
马东岳,王福,杜冠潮,王浩,王安民,常洪源,吕珲..基于"肾虚毒瘀"理论探讨通精解毒方在弱精子症中的应用[J].北京中医药大学学报,2025,48(5):664-668,5.基金项目
国家自然科学基金面上项目(No.82174217) （No.82174217）
国家中医药管理局高水平中医药重点学科建设项目(No.zyyzdxk-2023238) （No.zyyzdxk-2023238）
中国中医科学院西苑医院能力提升项目(No.XYZX0304-01) National Natural Science Foundation of China(No.82174217) （No.XYZX0304-01）
