摘要
Abstract
Objective:To explore the influencing factors of the onset of metabolic dysfunction-associated fatty liver disease(MAFLD).Methods:Two hundred residents of Shangrao City who underwent physical examinations in our hospital from January 2020 to June 2023 were selected.A self-designed epidemiological questionnaire was used to investigate the conditions including living habits and chronic diseases.The clinical data such as the laboratory test results,ultrasound examination results and Helicobacter pylori(Hp)infection detection results of the research group were collected.According to the results of abdominal B-ultrasound examination,the patients were divided into the MAFLD group(n=75)and the healthy physical examination group(n=125).The general data of the two groups were compared.Taking whether MAFLD was present as the dependent variable and the variables with statistical differences in the univariate analysis as the independent variables,multivariate Logistic regression analysis was conducted.Results:⑴ The number of patients in the MAFLD group with hypertension,diabetes,and Hp infection was all higher than that in the healthy physical examination group.Age,mean blood pressure(MBP),body weight,and body mass index BMI,waist circumference,fasting blood glucose(FBG),total cholesterol(TC),triglyceride(TG),high-density lipoprotein cholesterol(HDL-C),aspartate transferase(AST),alanine amino-transferase(ALT)and gamma-glutamyl transferase(GGT)were higher than those in the healthy physical examination group(P＜0.05).The level of low-density lipoprotein cholesterol(LDL-C)in the MAFLD group was lower than that in the healthy physical examination group(P＜0.05).Multivariate Logistic regression analysis was made and the results showed that BMI,FBG,TC,TG,HDL-C,LDL-C and Hp infection were risk factors for MAFLD(P＜0.05).Conclusion:BMI,FBG,TC,TG,HDL-C,LDL-C and Hp infection are risk factors for MAFLD.关键词
代谢相关脂肪性肝病/幽门螺杆菌/13C-尿素呼气试验检测Key words
Metabolic dysfunction-associated fatty liver disease/Helicobacter pylori/13C-urea breath test detection分类
临床医学
