河北医学2025，Vol.31Issue(5)：806-811,6.DOI:10.3969/j.issn.1006-6233.2025.05.018
老年肌少症与吞咽功能障碍发生的关系及高压氧辅助治疗效果观察
Relationship between Elderly Sarcopenia and Occurrence of Swallowing Dysfunction and Effect of Hyperbaric Oxygen Adjuvant Therapy
摘要
Abstract
Objective:To observe the relationship between elderly sarcopenia and swallowing dysfunc-tion and analyze the effect of hyperbaric oxygen(HBO)adjuvant therapy.Methods:Totally 120 elderly pa-tients with sarcopenia in the hospital from January 2022 to December 2023 were selected as the research sub-jects,and they received water swallow test.The occurrence of swallowing dysfunction was observed.The eld-erly patients with sarcopenia complicated with swallowing dysfunction were randomized into two groups.The control group adopted neuromuscular electrical stimulation,whereas the observation group received HBO adju-vant therapy on the basis of the control group.The levels of serum nutritional indexes[albumin(ALB),transferrin(TF)],modified Mann assessment of swallowing ability(MMASA),functional oral intake scale(FOIS)and swallowing-quality of life questionnaire(SWAL-QOL)were compared between groups at differ-ent time points.Results:Among the 120 elderly patients with sarcopenia,66 cases were combined with dys-phagia,the detection rate was 55.00%.66 elderly patients with sarcopenia complicated with swallowing dys-function were divided into control group(n=33)and observation group(n=33)by simple randomization method.At 3 weeks of treatment and at the end of treatment,serum ALB and TF levels in both groups were risen compared with those before treatment(P<0.05).The level of serum ALB in the observation group was higher than that in the control group at 3 weeks of treatment(P<0.05),and serum TF level was not statisti-cally different from that in the control group(P>0.05),and the levels of serum ALB and TF at the end of treatment were higher compared with those in the control group(P<0.05).The swallowing function-related scores(MMASA,FOIS,SWAL-QOL)in both groups were enhanced at 3 weeks of treatment and at the end of treatment compared with those before treatment,and the observation group had higher scores(P<0.05).Conclusion:Elderly patients with sarcopenia are prone to swallowing dysfunction.After HBO adjuvant thera-py,the swallowing function and nutritional status of elderly sarcopenia patients with swallowing dysfunction are significantly improved.关键词
老年肌少症/吞咽功能障碍/高压氧/疗效Key words
Elderly sarcopenia/Swallowing dysfunction/Hyperbaric oxygen/Efficacy引用本文复制引用
任珏辉,鲁燕,王妍,顾言,万莹,赵艺,陈玲..老年肌少症与吞咽功能障碍发生的关系及高压氧辅助治疗效果观察[J].河北医学,2025,31(5):806-811,6.基金项目
江苏省卫生健康委科研项目,(编号:Z2021088) （编号:Z2021088）
