四川大学学报（医学版）2025，Vol.56Issue(2)：584-590,7.DOI:10.12182/20250360609
颅骨干细胞的研究进展
Advances in the Study of Calvarial Stem Cells
摘要
Abstract
Calvarial stem cells are essential for maintaining the health and function of the craniofacial complex and the central nervous system.Under physiological conditions,these stem cells primarily reside within specialized microenvironments known as stem cell niches,located in the bone marrow,periosteum,and sutures of cranial bones.The heterogeneous cellular populations within the microenvironment dynamically regulate the quantity and function of stem cells.Due to their distinct spatial distribution,these stem cells exhibit unique functional characteristics and play crucial roles in the development and progression of various diseases,as well as in relevant therapeutic applications.Herein,we summarize the latest research advances concerning various types of calvarial stem cells,elaborating on their respective functions,microenvironmental regulation,and therapeutic potential,thereby providing new perspectives for both basic research and clinical applications in this field.关键词
颅骨/干细胞/干细胞龛/异质性/调控/综述Key words
Skull/Stem cells/Stem cell niches/Heterogeneity/Regulation/Review引用本文复制引用
李轩,靖军军,袁泉..颅骨干细胞的研究进展[J].四川大学学报（医学版）,2025,56(2):584-590,7.基金项目
国家自然科学基金(No.82125006)资助 （No.82125006）
