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基于边缘和位置信息的细胞核分割方法

贾伟 江海峰 赵雪芬

计算机应用与软件2025,Vol.42Issue(5):191-197,7.
计算机应用与软件2025,Vol.42Issue(5):191-197,7.DOI:10.3969/j.issn.1000-386x.2025.05.026

基于边缘和位置信息的细胞核分割方法

NUCLEI SEGMENTATION METHOD BASED ON EDGE AND POSITION INFORMATION

贾伟 1江海峰 2赵雪芬3

作者信息

  • 1. 宁夏大学信息工程学院 宁夏银川 750021
  • 2. 宁夏医科大学总医院病理科 宁夏银川 750021
  • 3. 宁夏大学新华学院 宁夏银川 750021
  • 折叠

摘要

Abstract

Aimed at the problem of poor segmentation accuracy due to fuzzy edge of nuclei and overlapping nuclei,an edge and position information-based nuclei segmentation method is proposed.The proposed method used the nuclei edge enhancement network to obtain and enhance the boundary information of the mask,and used the enhanced edge information to guide the encoder of convolutional neural network to extract the edge information.In the encoder,the edge refinement module was used to obtain more accurate nuclei edge.Between the encoder and the decoder,the position information was obtained through the dual attention mechanism.In network training,the loss function combined with edge information was used.The experimental results show that this method can improve the accuracy of nuclear segmentation by using edge and position information.

关键词

边缘/位置/细胞核分割/注意力

Key words

Edge/Position/Nuclei segmentation method/Attention

分类

计算机与自动化

引用本文复制引用

贾伟,江海峰,赵雪芬..基于边缘和位置信息的细胞核分割方法[J].计算机应用与软件,2025,42(5):191-197,7.

基金项目

国家自然科学基金项目(62062057) (62062057)

宁夏自然科学基金项目(2020AAC03032). (2020AAC03032)

计算机应用与软件

OA北大核心

1000-386X

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