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基于SNP推断表型的法庭科学研究进展与展望

周玲 康霞 王艳

解放军医学院学报2025,Vol.46Issue(1):37-42,60,7.
解放军医学院学报2025,Vol.46Issue(1):37-42,60,7.DOI:10.12435/j.issn.2095-5227.24090801

基于SNP推断表型的法庭科学研究进展与展望

Research advances and prospect in SNP phenotyping in forensic science

周玲 1康霞 2王艳1

作者信息

  • 1. 解放军总医院医学创新研究部,北京 100853||山西医科大学法医学院,山西 太原 030001
  • 2. 解放军总医院医学创新研究部,北京 100853
  • 折叠

摘要

Abstract

With the enhancement of the suspect's counter-surveillance ability and the increase of the complexity of the samples,forensic DNA phenotypic inference has been explored in the disciplinary applications,among which single nucleotide polymorphism(SNP)has shown great potential for development in courtroom science by virtue of the advantages of its small fragment size and multiple methods,which is expected to push courtroom science to a new height.However,due to the immaturity of related technology and analysis methods,it needs a lot of experimental research to improve its accuracy to reach the standard of practical application.The progress of SNP inferred phenotypes,the challenges and future prospects of SNPs in terms of pigmentation,height,facial features,male pattern baldness,etc.are discussed in this paper,so as to provide references for the application of SNPs in courtroom science.

关键词

单核苷酸多态性/法医遗传学/表型推断/法庭科学

Key words

single nucleotide polymorphism/forensic genetics/phenotypic inference/courtroom science

分类

医药卫生

引用本文复制引用

周玲,康霞,王艳..基于SNP推断表型的法庭科学研究进展与展望[J].解放军医学院学报,2025,46(1):37-42,60,7.

基金项目

法医遗传学公安部重点实验室开放课题(2024FGKFKT07) (2024FGKFKT07)

解放军医学院学报

2095-5227

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