中南医学科学杂志2025，Vol.53Issue(3)：439-441,445,4.DOI:10.15972/j.cnki.43-1509/r.2025.03.014
胸椎旁神经阻滞复合全麻在OPCABG患者中的临床应用效果
Clinical effect of thoracic paravertebral block combined with general anesthesia in OPCABG patients
摘要
Abstract
Aim To analyze clinical effect of thoracic paravertebral block(TPVB)combined with general anesthesia in pa-tients undergoing off-pump coronary artery bypass grafting(OPCABG).Methods According to different anesthesia methods,100 patients undergoing OPCABG were divided into general anesthesia group(general anesthesia)and combination group(TPVB combined with general anesthesia).Stress indexes,pain level,postoperative recovery time,cognitive function and occurrence of adverse reac-tions were compared between the two groups before and after surgery.Results Compared with preoperative baselines,NE,Cor and ACTH at 1d after surgery,and VAS scores at 1 d and 3 d after surgery,were increased in both groups,and these parameters were lower in combination group than general anesthesia group(P＜0.05).MoCA scores were decreased in both groups after surgery,and the scores were the lowest at 1d after surgery.Furthermore,MoCA score in combination group was higher than that in general anes-thesia group(P＜0.05).The postoperative stay time in ICU,first exhaust time and length of hospital stay in combination group were shorter than those in general anesthesia group(P＜0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion TPVB combined with general anesthesia can more effectively improve analgesic effect,relieve postoperative stress response and promote recovery in OPCABG patients.关键词
非体外循环冠状动脉旁路移植术/胸椎旁神经阻滞/全身麻醉/应激反应Key words
off-pump coronary artery bypass grafting/thoracic paravertebral block/general anesthesia/stress response分类
医药卫生引用本文复制引用
王艳丽,王梦迪,张志润,何会珍..胸椎旁神经阻滞复合全麻在OPCABG患者中的临床应用效果[J].中南医学科学杂志,2025,53(3):439-441,445,4.基金项目
河北省医学科学研究课题(20241636) （20241636）
