日用化学工业（中英文）2025，Vol.55Issue(5)：548-553,6.DOI:10.3969/j.issn.2097-2806.2025.05.002
MOFs功能化三聚氰胺海绵柱结合高效液相色谱法测定化妆品中对羟基苯甲酸酯类防腐剂
MOFs-Functionalized melamine sponge columns combined with high-performance liquid chromatography for determination of parabens in cosmetics
摘要
Abstract
This study developed a high-performance liquid chromatography(HPLC)method that leverages a functionalized melamine sponge as a sample pre-treatment material for the quantitative determination of paraben preservatives(PBs)in cosmetics.Utilizing the adhesive properties of polyvinylidene fluoride,the metal-organic framework material,MIL-68(Al),was effectively combined with melamine sponge(MeS)to create an efficient adsorbent,MIL-68(Al)/MeS.This novel material was used as a solid-phase extraction medium to isolate and quantify four types of PBs from various cosmetic samples.The method demonstrates excellent analytical performance,characterized by detection limits ranging from 0.24 to 0.43 ng/mL and a broad linear range of 5.00 to 200.00 ng/mL.The developed method exhibits robust intra-day and inter-day precision with recovery rates between 91.8％-98.4％and 101.4％-107.9％,respectively,and maintained a relative standard deviation(RSD)below 11.6％.Notably,this analytical procedure eliminates the need for centrifugation and filtration steps,significantly simplifying the sample preparation process while ensuring high recovery rates.The MIL-68(Al)/MeS composite is not only effective in adsorbing the target analytes but also enhances the efficiency of the extraction process.By reducing the complexity and time required for sample preparation,this method offers a practical and effective approach to ensuring product safety and compliance with regulatory standards.It also holds potential as an educational tool in analytical chemistry,providing a hands-on experience for undergraduate students through innovative experiments.关键词
对羟基苯甲酸酯/化妆品/功能化三聚氰胺海绵/样品前处理/高效液相色谱法Key words
parabens/cosmetics/functionalized melamine sponge/sample pre-treatment/HPLC分类
化学工程引用本文复制引用
马品一,李靖康,高德江,宋大千..MOFs功能化三聚氰胺海绵柱结合高效液相色谱法测定化妆品中对羟基苯甲酸酯类防腐剂[J].日用化学工业（中英文）,2025,55(5):548-553,6.基金项目
国家自然科学基金项目(22074052,22004046) （22074052,22004046）
吉林省科技发展计划项目(20230505010ZP) （20230505010ZP）
