上海护理2025，Vol.25Issue(6)：19-24,6.DOI:10.3969/j.issn.1009-8399.2025.06.004
老年精神分裂症患者日常自理能力与认知功能的交叉滞后分析
Cross-Lagged Analysis of Activities of Daily Living and Cognitive Function in Elderly Schizophrenia Patients
摘要
Abstract
Objective To explore the change trends and interaction effects between activities of daily living(ADL)and cognitive function in elderly schizophrenia patients over time.Methods A total of 286 elderly schizophrenia patients hospitalized at the Third People's Hospital of Ganzhou from April 2021 to April 2024 were selected by convenience sampling.Enrolled patients were evaluated for ADL and cognitive function using the Barthel Index(BI)and Montreal Cognitive Assessment(MoCA)at discharge(T1),3 months post-discharge(T2)and 6 months post-discharge(T3).The Pearson correlation test was conducted to analyze the correlation between ADL and cognitive function.A cross-lagged model was constructed based on Mplus to analyze the temporal causality and direction of effect between these two factors.Results A total of 254 patients(88.81%)completed three surveys and all assessments.For the 254 elderly schizophrenia patients,their BI scores at T1,T2 and T3 were(73.41±9.25)points,(71.88±8.92)points and(68.11±8.66)points,and MoCA scores at T1,T2 and T3 were(24.55±2.98)points,(23.27±2.77)points and(21.63±2.40)points,respectively.Correlation analysis revealed a positive correlation between BI scores and MoCA scores across all time points(T1,T2,T3)(all P<0.05).Cross-lagged analysis showed that ADL at T1 and T2 positively predicted cognitive function at T2 and T3(r1=0.054,r2=0.152,P<0.05),respectively;cognitive function at T1 and T2 positively predicted ADL at T2 and T3(r1=1.417,r2=1.220,P<0.05),respectively.Conclusion There are cross-lagged effects between ADL and cognitive function in elderly schizophrenia patients.Healthcare providers may use this relationship to develop targeted post-discharge care strategies for these patients to improve their prognosis.关键词
精神分裂症/老年/日常自理能力/认知功能/交叉滞后分析Key words
Schizophrenia/Elderly/Activities of daily living/Cognitive function/Cross-lagged analysis分类
临床医学引用本文复制引用
陈称美,王琴,朱可洲,谢贤炜..老年精神分裂症患者日常自理能力与认知功能的交叉滞后分析[J].上海护理,2025,25(6):19-24,6.基金项目
2022年度赣州市指导性科技计划项目(20222ZDX9553). （20222ZDX9553）
