医药导报2025，Vol.44Issue(6)：917-923,7.DOI:10.3870/j.issn.1004-0781.2025.06.013
组学技术在中药抗感染研究中的应用
Application of Omics Technologies in the Study of Traditional Chinese Medicine's Anti-infective Properties
孙怀远 1李文跃 2冯佳佳 1孔维华 1江坤 1林丽开1
作者信息
- 1. 武汉大学医院管理研究所,武汉 430071
- 2. 杭州胡庆余堂药业有限公司,杭州 310000
- 折叠
摘要
Abstract
Traditional Chinese medicine(TCM)has been used for the control and prevention of infectious diseases for thousands of years.Due to its characteristics of multiple components and multiple targets,it shows promising therapeutic prospects in the field of anti-infection.Here,we provide a detailed introduction to the current application of various omics technologies,such as metabolomics,proteomics,genomics,and transcriptomics in the study of TCM's anti-infective properties.The application of omics technologies can help explore the active components and their targets in TCM that contribute to its anti-infective effects;elucidate the biosynthetic pathways of active components,aiding in the discovery of new active ingredients;and investigate the mechanisms by which TCM affects pathogenic microorganisms,as well as interpret the mechanisms of TCM's synergy with antibiotics.As more research findings are produced and validated,the role of TCM in addressing the global challenge of antimicrobial resistance will become increasingly prominent through the integration of multi-omics and multidisciplinary research methods in the future.关键词
中药抗感染作用/组学技术/抗感染Key words
Anti-infective effect of traditional Chinese medicine/Omics technology/Anti-infective分类
中医学引用本文复制引用
孙怀远,李文跃,冯佳佳,孔维华,江坤,林丽开..组学技术在中药抗感染研究中的应用[J].医药导报,2025,44(6):917-923,7.
