中国临床药学杂志2025，Vol.34Issue(5)：376-382,7.DOI:10.19577/j.1007-4406.2025.05.010
慢性阻塞性肺疾病患者吸入药物用药依从性现状调查和影响因素分析
Analysis of current status and influencing factors of adherence to inhaled medications in patients with chronic obstructive pulmonary disease
张捷青 1叶晓芬 1吕迁洲 1李晓宇 1蔡青青 1陈淑靖2
作者信息
- 1. 复旦大学附属中山医院药剂科,上海 200032
- 2. 复旦大学附属中山医院呼吸与危重症医学科,上海 200032
- 折叠
摘要
Abstract
AIM The study extends previous research by examining the current status of adherence to inhaled medication and analyzing its influencing factors among adult Chinese patients with chronic obstructive pulmonary disease(COPD).METHOD The survey enrolled 200 COPD outpatients from the COPD specialty clinic between February 2021 and February 2022.Data on adherence to inhaled medications,beliefs about pharmacotherapy,and the impact of COPD on quality of life were assessed using the medication adherence report scale(MARS),beliefs about medicines questionnaire(BMQ),and COPD assessment test(CAT),respectively.Face-to-face interviews were conducted to collect these data.Baseline patient characteristics were analyzed with chi-square tests,and multivariable logistic regression was employed to identify influencing factors.RESULTS Among 200 COPD patients,79.5％exhibited high adherence to inhaled medication regimens.Based on adherence levels,they were categorized into high-adherence(n=159)and low-adherence(n=41)groups.The necessity score of the BMQ was significantly higher in the high-adherence group compared to the low-adherence group(P＜0.01).The concern score was significantly lower in the high-adherence group compared to the low-adherence group(P＜0.01).Multivariable analysis revealed that BMQ necessity scores,BMQ concern scores,and CAT total scores were independent influencing factors of adherence to inhaled medications(P＜0.05).CONCLUSION Clinical pharmacist should evaluate the patients' drug beliefs,pay attention to their medication compliance,improved medication adherence in COPD patients can be achieved by enhancing the medication beliefs and reducing anxiety.关键词
慢性阻塞性肺疾病/吸入药物/依从性/药物治疗信念/慢性阻塞性肺疾病评估测试/问卷调查Key words
chronic obstructive pulmonary disease/inhaled medication/adherence/beliefs about medicines/chronic obstructive pulmonary disease assessment test/questionnaire分类
药学引用本文复制引用
张捷青,叶晓芬,吕迁洲,李晓宇,蔡青青,陈淑靖..慢性阻塞性肺疾病患者吸入药物用药依从性现状调查和影响因素分析[J].中国临床药学杂志,2025,34(5):376-382,7.
