中国普通外科杂志2025，Vol.34Issue(4)：745-752,8.DOI:10.7659/j.issn.1005-6947.240421
腹腔镜胃癌术后近期感染性并发症的危险因素:单中心1572例回顾性分析
Risk factors for early postoperative infectious complications following laparoscopic gastrectomy:a single-center retrospective analysis of 1 572 cases
摘要
Abstract
Background and Aims:Minimally invasive surgery,represented by laparoscopic techniques,plays a vital role in the treatment of gastric cancer.However,postoperative infectious complications remain a key factor affecting patient recovery and prognosis.This study was performed to identify the risk factors associated with early(≤1 month)infectious complications after laparoscopic surgery for gastric cancer,providing a reference for clinical prevention strategies. Methods:A retrospective analysis was conducted on 1 572 patients who underwent laparoscopic surgery for gastric cancer at the First Affiliated Hospital of Xi'an Jiaotong University from March 2020 to February 2024.Patients were divided into infection and non-infection groups based on the occurrence of postoperative infectious complications.Univariate and multivariate Logistic regression analyses were performed to identify related risk factors. Results:Among the 1 572 patients,194 cases(12.3％)developed early postoperative infectious complications,including intra-abdominal infections(4.1％),surgical site infections(3.7％),and pulmonary infections(5.6％).Univariate analysis revealed that a history of diabetes,pulmonary disease,smoking,and preoperative anemia and hypoalbuminemia were significantly associated with postoperative infections(all P＜0.05).Multivariate analysis indicated that a history of diabetes(OR=6.927,95％CI=4.194-12.935),smoking(OR=3.079,95％CI=2.261-4.913),and preoperative albumin＜35 g/L(OR=0.572,95％CI=0.302-1.578)were independent risk factors for early postoperative infectious complications. Conclusion:A history of diabetes,smoking,and preoperative hypoalbuminemia are closely associated with the occurrence of early postoperative infectious complications after laparoscopic gastric cancer surgery.Clinical attention should be paid to perioperative metabolic,nutritional,and lifestyle management,and early intervention for high-risk patients may help reduce the incidence of complications,improve recovery,and enhance treatment outcomes.关键词
胃肿瘤/手术后并发症/感染/危险因素Key words
Stomach Neoplasms/Postoperative Complications/Infections/Risk Factors分类
临床医学引用本文复制引用
吴兴安,廖新华,仇广林,王海江,朱梦柯,卢婧,樊林,车向明..腹腔镜胃癌术后近期感染性并发症的危险因素:单中心1572例回顾性分析[J].中国普通外科杂志,2025,34(4):745-752,8.基金项目
国家自然科学基金资助项目(81472245). （81472245）
