中国普通外科杂志2025，Vol.34Issue(4)：787-795,9.DOI:10.7659/j.issn.1005-6947.250049
胃黏液腺癌的临床特征、分子机制及诊疗进展
Clinical characteristics,molecular mechanisms,and progress in diagnosis and treatment of mucinous gastric adenocarcinoma
摘要
Abstract
Mucinous gastric adenocarcinoma(MGC)is a distinct but under-researched subtype of gastric cancer,accounting for approximately 2.2％to 6.8％of all cases.It is characterized by the presence of ≥50％extracellular mucin within the tumor tissue.Although recognized as an independent subtype by international classification standards,significant controversies persist regarding the definition criteria,clinical prognosis,and treatment strategies of MGC.This article systematically reviews the epidemiological features,histological evolution,molecular mechanisms,and imaging characteristics of MGC,with a particular focus on the key issues related to definitional discrepancies,prognostic contradictions,and therapeutic challenges.Addressing these issues may provide references for optimizing clinical diagnosis and treatment,promote the development of individualized therapeutic strategies for MGC,and offer theoretical support for reducing global disparities in gastric cancer management.关键词
胃肿瘤/腺癌,黏液/预后/综述Key words
Stomach Neoplasms/Adenocarcinoma,Mucinous/Prognosis/Review分类
医药卫生引用本文复制引用
罗雨琛,黄秋林..胃黏液腺癌的临床特征、分子机制及诊疗进展[J].中国普通外科杂志,2025,34(4):787-795,9.基金项目
湖南省卫生健康高层次人才重大科研专项基金资助项目(20231526). （20231526）
