中国实验动物学报2025,Vol.33Issue(4):561-566,6.DOI:10.3969/j.issn.1005-4847.2025.04.010
斑马鱼在抗肿瘤药物和临床研究中的应用
Zebrafish applications in anti-tumor drug research and clinical studies
摘要
Abstract
Zebrafish is a relatively new experimental animal model with unique characteristics that enable its wide use in research on many human diseases.The exploration of anti-tumor drugs and other clinical treatments remain the focus of current research on cancer.Zebrafish characteristics,including rapid development,ease of observation,high genetic homology,and low-cost gene editing,make them highly useful for tumor research.By covering the applications of zebrafish in anti-tumor drug research and clinical studies,this review aims to provide valuable insights for the further utilization of zebrafish in cancer drug screening,assessment of drug activity and toxicity,and clinical research.关键词
斑马鱼/抗肿瘤/药物/筛选/耐药性/临床治疗Key words
zebrafish/anti-tumor/drug/screening/drug resistance/clinic therapy分类
生物学引用本文复制引用
李璘,邱蓉丽,魏凯峰,程海波,孙东东..斑马鱼在抗肿瘤药物和临床研究中的应用[J].中国实验动物学报,2025,33(4):561-566,6.基金项目
国家自然科学基金(82361168663),江苏省中医药科技发展计划重点项目(ZD202201).Funded by National Natural Science Foundation of China(82361168663),Key Project of Jiangsu Provincial Development Plan for Traditional Chinese Medicine Science and Technology(ZD202201). (82361168663)