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斑马鱼在抗肿瘤药物和临床研究中的应用

李璘 邱蓉丽 魏凯峰 程海波 孙东东

中国实验动物学报2025,Vol.33Issue(4):561-566,6.
中国实验动物学报2025,Vol.33Issue(4):561-566,6.DOI:10.3969/j.issn.1005-4847.2025.04.010

斑马鱼在抗肿瘤药物和临床研究中的应用

Zebrafish applications in anti-tumor drug research and clinical studies

李璘 1邱蓉丽 2魏凯峰 1程海波 3孙东东3

作者信息

  • 1. 南京中医药大学中医学院,南京 210023
  • 2. 南京中医药大学药学院,南京 210023
  • 3. 南京中医药大学江苏省中医药防治肿瘤协同创新中心,南京 210023
  • 折叠

摘要

Abstract

Zebrafish is a relatively new experimental animal model with unique characteristics that enable its wide use in research on many human diseases.The exploration of anti-tumor drugs and other clinical treatments remain the focus of current research on cancer.Zebrafish characteristics,including rapid development,ease of observation,high genetic homology,and low-cost gene editing,make them highly useful for tumor research.By covering the applications of zebrafish in anti-tumor drug research and clinical studies,this review aims to provide valuable insights for the further utilization of zebrafish in cancer drug screening,assessment of drug activity and toxicity,and clinical research.

关键词

斑马鱼/抗肿瘤/药物/筛选/耐药性/临床治疗

Key words

zebrafish/anti-tumor/drug/screening/drug resistance/clinic therapy

分类

生物学

引用本文复制引用

李璘,邱蓉丽,魏凯峰,程海波,孙东东..斑马鱼在抗肿瘤药物和临床研究中的应用[J].中国实验动物学报,2025,33(4):561-566,6.

基金项目

国家自然科学基金(82361168663),江苏省中医药科技发展计划重点项目(ZD202201).Funded by National Natural Science Foundation of China(82361168663),Key Project of Jiangsu Provincial Development Plan for Traditional Chinese Medicine Science and Technology(ZD202201). (82361168663)

中国实验动物学报

OA北大核心

1005-4847

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