中国实用内科杂志2025，Vol.45Issue(5)：373-380,8.DOI:10.19538/j.nk2025050104
中国结直肠癌早筛早诊早治高质量发展的思考
Perspectives on high-quality development of early screening,early diagnosis,and early treatment for colorectal cancer in China
摘要
Abstract
The incidence and mortality rates of colorectal cancer in China have been increasing annually,with marked urban-rural and regional disparities.In recent years,important progress has been made in early colorectal cancer screening,leading to the preliminary establishment of a screening model suitable for the national context.This model centers on a"two-step"screening strategy,which involves initial screening through risk assessment questionnaires,fecal immunochemical testing(FIT),and fecal DNA testing,followed by colonoscopy for high-risk populations.However,current screening efforts still face challenges such as low public compliance,uneven distribution of endoscopic resources,and an incomplete screening system.With the rapid development of non-invasive screening technologies,including blood and fecal biomarker testing,the capability for early colorectal cancer screening and initial risk stratification has significantly improved.In the future,by integrating the advantages of colonoscopy with new non-invasive technologies and establishing dynamic risk assessment models and multi-dimensional screening systems,the efficiency of early screening will be further enhanced,and the rate of missed diagnoses will be reduced.This will provide crucial support for achieving high-quality development in the"early screening,early diagnosis,and early treatment"of colorectal cancer.关键词
结直肠癌/早期筛查/结肠镜/生物标志物/风险分层Key words
colorectal cancer/early screening/colonoscopy/biomarker/risk stratification分类
临床医学引用本文复制引用
赵英楠,高君妍,贺子轩,柏愚,李兆申..中国结直肠癌早筛早诊早治高质量发展的思考[J].中国实用内科杂志,2025,45(5):373-380,8.基金项目
科技创新2030重大项目子课题(2023ZD0501601) （2023ZD0501601）
国家自然科学基金(82170568,82300641) （82170568,82300641）
