摘要
Abstract
Objective:To observe the clinical effect of Qili Qiangxin Capsules in the adjuvant treatment of elderly patients with coronary heart disease(CHD)and chronic heart failure(CHF).Method:A total of 100 elderly patients with CHD and CHF who admitted to the Geriatrics Department of Yulin Yuyang District Traditional Chinese Medicine Hospital from January 2023 to January 2024 were selected,they were divided into the control group and the observation group according to the order of admission,50 cases in each group.The control group was treated with Spironolactone Tablets and Telmisartan Capsules,and the observation group was treated with Qili Qiangxin Capsules on the basis of the control group.The cardiac function,hemodynamics,heart failure markers,traditional Chinese medicine symptom scores,efficacy and adverse reactions were compared between two groups.Result:There were no significant differences in the cardiac function,hemodynamics,heart failure markers and traditional Chinese medicine symptom scores between two groups before treatment(P>0.05);after treatment,the indexes of two groups were improved compared with those before treatment,and the left ventricular end-diastolic diameter(LVEDD),left ventricular end-systolic diameter(LVESD),hemodynamic indexes,N-terminal pro-brain natriuretic peptide(NT-proBNP),soluble growth stimulation expression gene 2 protein(sST2)and traditional Chinese medicine syndrome scores in the observation group were lower than those in the control group,while the left ventricular ejection fraction(LVEF),vascular endothelial growth factor(VEGF)and total effective rate were higher than those in the control group,the differences were statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between two groups(P>0.05).Conclusion:Qili Qiangxin Capsules can effectively improve cardiac function and repair heart failure in elderly patients with CHD and CHF,the clinical efficacy is good and safe and reliable.关键词
冠心病/心力衰竭/芪苈强心胶囊/螺内酯/替米沙坦/血流动力学Key words
Coronary heart disease/Heart failure/Qili Qiangxin Capsule/Spironolactone/Telmisartan/Hemodynamics
