摘要
Abstract
Objective:To investigate high-resolution computed tomography(HRCT)imaging features of visceral pleural invasion(VPI)of lung adenocarcinoma manifesting as subsolid nodule(SSN),and its influencing factors.Method:From June 2021 to June 2024,92 patients with lung adenocarcinoma manifesting as SSN who received treatment in Jingzhou Third People's Hospital were selected.They were divided into the non-VPI group and the VPI group according to whether they developed VPI.Both groups underwent HRCT examination,and imaging features of the two groups,including lesion location,lesion morphology,maximum diameter of the solid part of the tumor,tumor edge signs(spicule sign and lobulation sign),tumor internal signs(vacuolar sign),adjacent tissue signs(pleural indentation)and nodule and pleura relationship(NPR)were compared.Result:Among the study subjects,36 patients developed VPI,accounting for 39.13%.There was no statistically significant difference between the non-VPI group and the VPI group in terms of lesion location,lesion morphology,and the proportion of lobulation signs(P>0.05).The maximum diameter of the solid part of the tumor>10 mm,and the proportions of spicule signs,vacuolar signs and pleural indentation in the VPI group were significantly larger and higher than those in the non-VPI group,the difference in NPR classification between the two groups was statistically significant(P<0.05).Multivariate regression analysis showed that the maximum diameter of the solid part of the tumor,spicule sign at the tumor edge,and NPR classification were independent influencing factors for the occurrence of VPI(P<0.05).Conclusion:HRCT imaging features of patients with lung adenocarcinoma manifesting as SSN are helpful for evaluating the occurrence of VPI.Among them,the maximum diameter of the solid part of the tumor,spicule sign at the tumor edge,and NPR classification are significantly related to the occurrence of VPI,which can provide important information for clinical diagnosis and evaluation.关键词
肺腺癌/亚实性结节/胸膜侵犯Key words
Lung adenocarcinoma/Subsolid nodule/Pleural invasion
