中外医学研究2025，Vol.23Issue(14)：124-126,3.DOI:10.14033/j.cnki.cfmr.2025.14.033
阿立哌唑、利培酮与氟哌啶醇治疗儿童抽动障碍的效果及安全性
Efficacy and Safety of Aripiprazole,Risperidone and Haloperidol in the Treatment of Children with Tic Disorders
李文汉 1吕波 1陈科飞 1冯子豪1
作者信息
- 1. 昭通市中医医院 云南 昭通 657000
- 折叠
摘要
Abstract
Objective:To explore the efficacy and safety of Aripiprazole,Risperidone and Haloperidol in the treatment of children with tic disorder.Method:A total of 96 children with tic disorder who diagnosed and treated in Zhaotong Traditional Chinese Medicine Hospital from March 2021 to March 2024 were selected,and they were randomly divided into Aripiprazole group,Risperidone group and Haloperidol group,with 32 cases in each group.The tic severity[Yale global tic severity scale(YGTSS)],clinical efficacy and adverse reactions were compared among three groups.Result:There were no significant differences in the YGTSS scores among three groups before treatment,4 weeks after treatment and 8 weeks after treatment(P>0.05);the YGTSS scores of three groups after 4 weeks and 8 weeks of treatment were lower than those before treatment,and the YGTSS scores of the three groups after 8 weeks of treatment were lower than those after 4 weeks of treatment,the differences were statistically significant(P<0.05).There was no significant difference in the total clinical effective rate among three groups(P>0.05).There was statistically significant difference in the incidence of adverse reactions among three groups(P<0.05).Conclusion:The use of Aripiprazole,Risperidone and Haloperidol in children with tic disorders is beneficial for improving their tic symptoms,however,compared to Risperidone and Haloperidol,Aripiprazole has fewer adverse reactions and is safer to treat.关键词
儿童抽动障碍/阿立哌唑/利培酮/氟哌啶醇/安全性Key words
Children with tic disorders/Aripiprazole/Risperidone/Haloperidol/Security引用本文复制引用
李文汉,吕波,陈科飞,冯子豪..阿立哌唑、利培酮与氟哌啶醇治疗儿童抽动障碍的效果及安全性[J].中外医学研究,2025,23(14):124-126,3.
