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枳实薤白桂枝汤治疗冠状动脉粥样硬化性心脏病的研究进展

邓怡雯 谈晓东

中医临床研究2025,Vol.17Issue(3):1-5,5.
中医临床研究2025,Vol.17Issue(3):1-5,5.DOI:10.3969/j.issn.1674-7860.2025.03.001

枳实薤白桂枝汤治疗冠状动脉粥样硬化性心脏病的研究进展

Research progress of Zhishi Xiebai Guizhi decoction in treating coronary atherosclerotic heart disease

邓怡雯 1谈晓东1

作者信息

  • 1. 无锡市中医医院/南京中医药大学无锡附属医院,江苏 无锡,214074
  • 折叠

摘要

Abstract

Coronary atherosclerotic heart disease refers to the heart disease caused by coronary atherosclerosis,which makes the lumen spasm,narrow or block,leading to myocardial ischemia and hypoxia,referred to as coronary heart disease.Acute coronary syndrome is a common clinical type of coronary heart disease,which is often life-threatening,poses a great threat to human health,and brings serious burden to families.Therefore,the prevention and treatment of ACS has been paid attention to in the medical field.Modern medicine believes that acute coronary syndrome is closely related to"vulnerable plaque",which is related to inflammation,endothelial function decline and lipid metabolism disorder in the body.Plaque accumulation is the central link of the occurrence and development of coronary heart disease,and the activity of vulnerable plaques is the key factor of acute cardiovascular events.For coronary heart disease,the common clinical treatment options include drug conservative treatment and surgical intervention.Drugs include lipid-regulating plaque stabilizing drugs,anti-platelet aggregation drugs,anticoagulant drugs,nitrates and so on.It is undeniable that Western medicine treatment is still accompanied by a certain degree of adverse reactions and drug resistance problems.The famous theory of"weak pulse at Yang(阳)and wiry pulse at Yin(阴)"in traditional Chinese medicine suggests that the pathogenesis of chest numbness and heartache is asthenia in origin and asthenia in superficiality,and phlegm turbidness is the main pathogenic factor,which is in harmony with the theory of"vulnerable plaque"in Western medicine.Zhishi Xiebai Guizhi decoction(枳实薤白桂枝汤)is a classic Chinese medicine prescription for treating coronary heart disease.It has the function of disperzing Yang,eliminating phlegm and regulating Qi(气).It is used to treat coronary heart disease with phlegm turbidity blocking,and has shown unique value and advantage in clinical application.Western medicine treats coronary heart disease from"vulnerable plaque",and Chinese medicine treats crown chest impediment and heartache from"phlegm turbidity",which complement each other.

关键词

冠状动脉粥样硬化性心脏病/急性冠脉综合征/枳实薤白桂枝汤/易损斑块

Key words

Coronary heart disease/Atherosclerosis/Zhishi Xiebai Guizhi decoction/Vulnerable plaque

分类

医药卫生

引用本文复制引用

邓怡雯,谈晓东..枳实薤白桂枝汤治疗冠状动脉粥样硬化性心脏病的研究进展[J].中医临床研究,2025,17(3):1-5,5.

中医临床研究

1674-7860

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