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人工冬眠诱导及其神经调控机制研究进展

罗林林 周雨曦 罗天元 喻田

遵义医科大学学报2025,Vol.48Issue(5):515-522,8.
遵义医科大学学报2025,Vol.48Issue(5):515-522,8.

人工冬眠诱导及其神经调控机制研究进展

Research progress of artificial hibernation technology and its central action mechanism

罗林林 1周雨曦 2罗天元 3喻田2

作者信息

  • 1. 遵义医科大学附属医院麻醉科,贵州遵义 563000||教育部麻醉与器官保护重点实验室-培育,贵州遵义 563000||遵义市播州区人民医院麻醉科,贵州遵义 563000
  • 2. 教育部麻醉与器官保护重点实验室-培育,贵州遵义 563000
  • 3. 遵义医科大学附属医院麻醉科,贵州遵义 563000||教育部麻醉与器官保护重点实验室-培育,贵州遵义 563000
  • 折叠

摘要

Abstract

Hibernation is a biological phenomenon in which animals respond to adverse environmental condi-tions through a highly conserved physiological adaptation mechanism.This phenomenon is characterized by the active downregulation of metabolic rate and core body temperature,accompanied by significantly suppressed be-havioral activity.Although humans lack the natural ability to hibernate,artificially induced hibernation has dem-onstrated significant potential in critical care organ protection,trauma recovery,and long-term space travel.In recent years,advancements in understanding the mechanisms underlying hibernation formation within the field of neuroscience have continuously emerged,driving the gradual development of artificial hibernation induction tech-nologies and highlighting their promising clinical application potential.This study provides a comprehensive re-view of artificial hibernation induction technologies and their neuroregulatory mechanisms,aiming to facilitate further research and development of hibernation mechanisms and artificial hibernation technologies in medicine and other fields.

关键词

冬眠/人工冬眠技术/神经机制/器官功能保护/太空航行

Key words

hibernation/artificial hibernation technology/central mechanism of action/organ function protec-tion/space travel

分类

生物学

引用本文复制引用

罗林林,周雨曦,罗天元,喻田..人工冬眠诱导及其神经调控机制研究进展[J].遵义医科大学学报,2025,48(5):515-522,8.

基金项目

国家自然科学基金资助项目(NO:82460707),贵州省大学生创新创业计划资助项目(NO:S2024106612227). (NO:82460707)

遵义医科大学学报

2096-8159

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