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首页|期刊导航|Acta Biochimica et Biophysica Sinica|Silencing of PCK1 mitigates the proliferation and migration of vascular smooth muscle cells and vascular intimal hyperplasia by suppressing STAT3/DRP1-mediated mitochondrial fission

Silencing of PCK1 mitigates the proliferation and migration of vascular smooth muscle cells and vascular intimal hyperplasia by suppressing STAT3/DRP1-mediated mitochondrial fission

Li Zhang Yingmei Chen Quanrong Pan Shizheng Fang Zhongjian Zhang Jia Wang Yongjian Yang Dachun Yang Xiongshan Sun

Acta Biochimica et Biophysica Sinica2025,Vol.57Issue(4):P.633-645,13.
Acta Biochimica et Biophysica Sinica2025,Vol.57Issue(4):P.633-645,13.DOI:10.3724/abbs.2024154

Silencing of PCK1 mitigates the proliferation and migration of vascular smooth muscle cells and vascular intimal hyperplasia by suppressing STAT3/DRP1-mediated mitochondrial fission

Li Zhang 1Yingmei Chen 1Quanrong Pan 2Shizheng Fang 3Zhongjian Zhang 1Jia Wang 1Yongjian Yang 1Dachun Yang 1Xiongshan Sun1

作者信息

  • 1. Department of Cardiology,the General Hospital of Western Theater Command,Chengdu 610083,China
  • 2. Department of General Practice,the General Hospital of Western Theater Command,Chengdu 610083,China
  • 3. Department of Critical Care Medicine,the General Hospital of Western Theater Command,Chengdu 610083,China
  • 折叠

摘要

关键词

phosphoenolpyruvate carboxyl kinase 1/vascular smooth muscle cells/mitochondrial fission/neointimal hyperplasia/dynamin-related protein 1

分类

医药卫生

引用本文复制引用

Li Zhang,Yingmei Chen,Quanrong Pan,Shizheng Fang,Zhongjian Zhang,Jia Wang,Yongjian Yang,Dachun Yang,Xiongshan Sun..Silencing of PCK1 mitigates the proliferation and migration of vascular smooth muscle cells and vascular intimal hyperplasia by suppressing STAT3/DRP1-mediated mitochondrial fission[J].Acta Biochimica et Biophysica Sinica,2025,57(4):P.633-645,13.

基金项目

supported by the grants from the National Natural Science Foundation of China(No.82100419 to X.S.) (No.82100419 to X.S.)

the General Hospital of Western Theater Command(No.2021-XZYG-A02 to D.Y.,No.2021-XZYG-C41 to X.S.) (No.2021-XZYG-A02 to D.Y.,No.2021-XZYG-C41 to X.S.)

the Foundation for″Tianfu″Talents from the Government of Sichuan Province(awarded to D.Y.). (awarded to D.Y.)

Acta Biochimica et Biophysica Sinica

1672-9145

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