Acta Biochimica et Biophysica Sinica2025，Vol.57Issue(4)：P.667-670,4.DOI:10.3724/abbs.2024179
A TRIM21-based method for targeted protein degradation
Weikang Hu 1Xiang Qiu 1Yun Yang 2Yaoyao Wu 3Chengcheng Wang 4Ronggui Hu 5Chuanyin Li6
作者信息
- 1. Medical College of Guizhou University,Guiyang 550025,China State Key Laboratory of Molecular Biology,Shanghai Institute of Biochemistry and Cell Biology,Center for Excellence in Molecular Cell Science,Chinese Academy of Sciences,Shanghai 200031,China
- 2. State Key Laboratory of Molecular Biology,Shanghai Institute of Biochemistry and Cell Biology,Center for Excellence in Molecular Cell Science,Chinese Academy of Sciences,Shanghai 200031,China Key Laboratory of Systems Health Science of Zhejiang Province,School of Life Science,Hangzhou Institute for Advanced Study,University of Chinese Academy of Sciences,Hangzhou 310024,China
- 3. Medical College of Guizhou University,Guiyang 550025,China Department of Respiratory and Critical Care Medicine,Guizhou Provincial People’s Hospital,Guiyang 550002,China
- 4. Medical College of Guizhou University,Guiyang 550025,China
- 5. Medical College of Guizhou University,Guiyang 550025,China State Key Laboratory of Molecular Biology,Shanghai Institute of Biochemistry and Cell Biology,Center for Excellence in Molecular Cell Science,Chinese Academy of Sciences,Shanghai 200031,China Key Laboratory of Systems Health Science of Zhejiang Province,School of Life Science,Hangzhou Institute for Advanced Study,University of Chinese Academy of Sciences,Hangzhou 310024,China Department of Colorectal Surgery and Oncology(Key Laboratory of Cancer Prevention and Intervention,China National Ministry of Education,Key Laboratory of Molecular Biology in Medical Sciences,Zhejiang Province,China),the Second Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310009,China
- 6. State Key Laboratory of Molecular Biology,Shanghai Institute of Biochemistry and Cell Biology,Center for Excellence in Molecular Cell Science,Chinese Academy of Sciences,Shanghai 200031,China Department of Colorectal Surgery and Oncology(Key Laboratory of Cancer Prevention and Intervention,China National Ministry of Education,Key Laboratory of Molecular Biology in Medical Sciences,Zhejiang Province,China),the Second Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310009,China
- 折叠
摘要
关键词
trim/degrading intracellular proteins/life processes dysfunction/neurodegenerative diseases targeted protein degradation tpd technologies/clinical interventions recentl/targeted protein degradation/biological research/protein degradation pathway分类
医药卫生引用本文复制引用
Weikang Hu,Xiang Qiu,Yun Yang,Yaoyao Wu,Chengcheng Wang,Ronggui Hu,Chuanyin Li..A TRIM21-based method for targeted protein degradation[J].Acta Biochimica et Biophysica Sinica,2025,57(4):P.667-670,4.基金项目
supported by the grants from the National Science and Technology Innovation 2030 Major Project of China(No.2021ZD0203900) （No.2021ZD0203900）
the Ministry of Science and Technology of China(No.2019YFA0802103) （No.2019YFA0802103）
the National Natural Science Foundation of China(Nos.82304563 and 31900804) （Nos.82304563 and 31900804）
the Department of Science and Technology of Zhejiang Province(No.2021C03104) （No.2021C03104）
the Guangzhou Science Innovation and Development Program(No.201803010092) （No.201803010092）
the Shenzhen-Hong Kong Institute of Brain Science(No.NYKFKT2019006). （No.NYKFKT2019006）
