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NLRP3 inflammasome-mediated disruption of mitochondrial homeostasis in alveolar macrophages contributes to ozone-induced acute lung inflammatory injury

Xinyi Miao Xinling Li Pengwei Ma Mengyuan Li Yuting Jiang Pengpeng Wang Xiaolei Zhou Ling Wang Pingping Shang Qiao Zhang Feifei Feng

Acta Biochimica et Biophysica Sinica2025，Vol.57Issue(3)：P.463-472,10.

Acta Biochimica et Biophysica Sinica2025，Vol.57Issue(3)：P.463-472,10.DOI:10.3724/abbs.2024171

NLRP3 inflammasome-mediated disruption of mitochondrial homeostasis in alveolar macrophages contributes to ozone-induced acute lung inflammatory injury

Xinyi Miao ¹Xinling Li ²Pengwei Ma ¹Mengyuan Li ²Yuting Jiang ¹Pengpeng Wang ²Xiaolei Zhou ³Ling Wang ⁴Pingping Shang ⁵Qiao Zhang ¹Feifei Feng¹

作者信息

1. Department of Toxicology,College of Public Health,Zhengzhou University,Zhengzhou 450001,China
2. Department of Occupational and Environmental Health,College of Public Health,Zhengzhou University,Zhengzhou 450001,China
3. Department of Pulmonary Medicine,Chest Hospital of Zhengzhou University,Zhengzhou University,Zhengzhou 450000,China
4. Faculty of Medicine,Macao University of Science and Technology,Macao 999078,China
5. Key Laboratory of Tobacco Chemistry,Zhengzhou Tobacco Research Institute,CNTC,Zhengzhou 450001,China
折叠

摘要

关键词

ozone/acute lung inflammatory injury/alveolar macrophages/NLRP3 inflammasome/mitochondrial homeostasis

分类

医药卫生

引用本文复制引用

Xinyi Miao,Xinling Li,Pengwei Ma,Mengyuan Li,Yuting Jiang,Pengpeng Wang,Xiaolei Zhou,Ling Wang,Pingping Shang,Qiao Zhang,Feifei Feng..NLRP3 inflammasome-mediated disruption of mitochondrial homeostasis in alveolar macrophages contributes to ozone-induced acute lung inflammatory injury[J].Acta Biochimica et Biophysica Sinica,2025,57(3):P.463-472,10.

基金项目

supported by the grants from the National Natural Science Foundation of China(No.42377433) （No.42377433）

the Chief Scientist Innovation Project from China National Tobacco Corporation(No.322022CK0480) （No.322022CK0480）

the NHC Key Laboratory of Birth Defects Prevention(No.ZD202306) （No.ZD202306）

the Science and Technology Research Program of Henan Province(Nos.232102310496 and 232102311234). （Nos.232102310496 and 232102311234）

Acta Biochimica et Biophysica Sinica

ISSN：1672-9145

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