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Mitigating Ibrutinib-Induced Ventricular Arrhythmia and Cardiac Dysfunction With Metformin

Pengsha Li Daiqi Liu Pan Gao Ming Yuan Zhiqiang Zhao Yue Zhang Zandong Zhou Qingling Zhang Meng Yuan Xing Liu Gary Tse Guangping Li Qiankun Bao Tong Liu

Cancer Innovation2025，Vol.4Issue(1)：P.79-90,12.

Cancer Innovation2025，Vol.4Issue(1)：P.79-90,12.DOI:10.1002/cai2.151

Mitigating Ibrutinib-Induced Ventricular Arrhythmia and Cardiac Dysfunction With Metformin

Pengsha Li ¹Daiqi Liu ¹Pan Gao ¹Ming Yuan ²Zhiqiang Zhao ¹Yue Zhang ¹Zandong Zhou ¹Qingling Zhang ¹Meng Yuan ¹Xing Liu ¹Gary Tse ³Guangping Li ¹Qiankun Bao ¹Tong Liu¹

作者信息

1. Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease,Department of Cardiology,Tianjin Institute of Cardiology,Second Hospital of Tianjin Medical University,Tianjin,China
2. Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease,Department of Cardiology,Tianjin Institute of Cardiology,Second Hospital of Tianjin Medical University,Tianjin,China Key Laboratory of Cardiovascular Intervention and Regenerative Medicine of Zhejiang Province,Department of Cardiology,Sir Run Run Shaw Hospital,Zhejiang University School of Medicine,Hangzhou,China
3. Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease,Department of Cardiology,Tianjin Institute of Cardiology,Second Hospital of Tianjin Medical University,Tianjin,China Kent and Medway Medical School,Canterbury,UK
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摘要

关键词

Ibrutinib/metformin/PI3K-AKT pathway/ventricular arrhythmia

分类

医药卫生

引用本文复制引用

Pengsha Li,Daiqi Liu,Pan Gao,Ming Yuan,Zhiqiang Zhao,Yue Zhang,Zandong Zhou,Qingling Zhang,Meng Yuan,Xing Liu,Gary Tse,Guangping Li,Qiankun Bao,Tong Liu..Mitigating Ibrutinib-Induced Ventricular Arrhythmia and Cardiac Dysfunction With Metformin[J].Cancer Innovation,2025,4(1):P.79-90,12.

基金项目

National Natural Science Foundation of China(Grants:82170327,82200344,82370332) （Grants:82170327,82200344,82370332）

Tianjin Key Medical Discipline(Specialty)Construction Project(Grant:TJYXZDXK-029A) （Specialty）

Tianjin Natural Science Foundation(Grants:20JCZDJC00340,20JCZXJC00130). （Grants:20JCZDJC00340,20JCZXJC00130）

Cancer Innovation

ISSN：2770-9191

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