首页|期刊导航|Virologica Sinica|The SARS-CoV-2 NSP4 T492I mutation promotes double-membrane vesicle formation to facilitate transmission

The SARS-CoV-2 NSP4 T492I mutation promotes double-membrane vesicle formation to facilitate transmission

Pei Wang Buyun Tian Ke Xiao Wei Ji Zonghong Li

Virologica Sinica2025，Vol.40Issue(2)：P.225-235,11.

Virologica Sinica2025，Vol.40Issue(2)：P.225-235,11.DOI:10.1016/j.virs.2025.03.010

The SARS-CoV-2 NSP4 T492I mutation promotes double-membrane vesicle formation to facilitate transmission

Pei Wang ¹Buyun Tian ¹Ke Xiao ²Wei Ji ²Zonghong Li¹

作者信息

1. The First Affiliated Hospital of Guangzhou Medical University,Guangzhou National Laboratory Clinical Base,Guangzhou Medical University,Guangzhou,510120,China Guangzhou National Laboratory,Guangzhou,510005,China
2. National Laboratory of Biomacromolecules,CAS Center for Excellence in Biomacromolecules,Institute of Biophysics,Chinese Academy of Sciences,Beijing,100101,China
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摘要

关键词

SARS-CoV-2/Virus transmission/NSP4 T492I mutation/DMV/Homodimerization/ER membrane curvature

分类

医药卫生

引用本文复制引用

Pei Wang,Buyun Tian,Ke Xiao,Wei Ji,Zonghong Li..The SARS-CoV-2 NSP4 T492I mutation promotes double-membrane vesicle formation to facilitate transmission[J].Virologica Sinica,2025,40(2):P.225-235,11.

基金项目

supported by the National Natural Science Foundation of China(92469107 to Z.Li) （92469107 to Z.Li）

the R&D Program of Guangzhou National Laboratory(ZL-SRPG2200205 to Z.Li) （ZL-SRPG2200205 to Z.Li）

the Guangdong Province High-level Talent Youth Project(2021QN02Y939 to Z.Li). （2021QN02Y939 to Z.Li）

Virologica Sinica

ISSN：1674-0769

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