北京生物医学工程2025，Vol.44Issue(3)：229-236,8.DOI:10.3969/j.issn.1002-3208.2025.03.002
基于定向微波天线消融邻近重要组织肝肿瘤的温度场仿真研究
Temperature field simulation study of ablation of liver tumors adjacent to critical tissues based on directional microwave antennas
摘要
Abstract
Objective To explore the method of microwave ablation of liver tumors adjacent to gallbladder and blood vessels by directional antenna,and to provide research basis for its clinical application.Methods Firstly,3D simulation models of liver tumor adjacent to gallbladder and blood vessels were established,and the parameters of antenna insertion position and microwave ablation time were optimized by response surface method.Secondly,aiming at higher tumor ablation coverage and lower additional damage rate of adjacent tissues,and the optimal parameters were obtained.Finally,under the same experimental methods and conditions,the microwave ablation method using traditional omnidirectional antenna was simulated to verify the advantages of using directional antenna.Results The tumor was adjacent to gallbladder tissue,and the best tumor ablation coverage rate produced by directional antenna and omnidirectional antenna was 99.56%and 100%,respectively,and the gallbladder injury rate was 0 and 0.42%.When the tumor was adjacent to blood vessels,the coverage rate of tumor ablation was 94.16%and 99.45%respectively,and the vascular injury was 0 and 7.33%.Conclusions The asymmetric ablation area generated by directional antenna can be used to achieve high tumor ablation coverage for liver tumors adjacent to important tissues and avoid additional damage to surrounding tissues.关键词
定向天线/肝肿瘤/胆囊/血管/微波消融Key words
directional antenna/liver tumor/gallbladder/blood vessels/microwave ablation分类
医药卫生引用本文复制引用
刘慧慧,吴宁,高有增,南群..基于定向微波天线消融邻近重要组织肝肿瘤的温度场仿真研究[J].北京生物医学工程,2025,44(3):229-236,8.基金项目
国家自然科学基金(31771021、11832003)资助 （31771021、11832003）
