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基于近红外光谱的流化床制粒过程流化态值反馈控制系统的构建与性能评估

闫豪洁 陈杭 邱林钧 卢立明 瞿海斌

分析测试学报2025,Vol.44Issue(6):1169-1175,7.
分析测试学报2025,Vol.44Issue(6):1169-1175,7.DOI:10.12452/j.fxcsxb.250304140

基于近红外光谱的流化床制粒过程流化态值反馈控制系统的构建与性能评估

Construction and Performance Evaluation of Fluidization State Value Feedback Control System for Fluidized Bed Granulation Process Based on Near Infrared Spectroscopy

闫豪洁 1陈杭 2邱林钧 3卢立明 3瞿海斌1

作者信息

  • 1. 浙江大学 药学院,药物信息学研究所,浙江 杭州 310058||浙江大学智能创新药物研究院,浙江 杭州 310018
  • 2. 浙江大学 药学院,药物信息学研究所,浙江 杭州 310058
  • 3. 浙江派腾测控技术有限公司,浙江 杭州 311100
  • 折叠

摘要

Abstract

Fluidized bed granulation is widely used in the production of traditional Chinese medicine granules,but the traditional granulation process relies on the operator to observe the material state in the fluidized bed,and manually adjust the air volume and liquid injection speed according to experi-ence,which has the problems of time-consuming,labor-intensive and insufficient intelligent level.Therefore,this paper constructed a fluidization state value feedback control system based on near in-frared spectroscopy,and evaluated its control performance.The near infrared spectrum of the fluid-ized bed granulation process was collected in real time to analyze the movement state of the material and calculate the fluidization state value index.Then,the system automatically adjusted the peristal-tic pump speed in the spray system according to the fluidization state value index and the preset con-trol rules,thereby realizing the dynamic control of the spray speed and achieving the fluidization state value real-time feedback control.The experimental results show that the feedback control sys-tem can effectively prevent the occurrence of bed collapse when the fluidization state deteriorates.When the fluidization state value is good,the system can speed up the liquid spraying,thereby sav-ing the granulation time and improving the production efficiency.Compared with the manual control mode,the automatic control system reduced the liquid injection time by more than 20%.In terms of fluidization state value control,the system is equivalent to the manual control,while it shows signifi-cant advantages in the optimization of liquid injection time.In addition,the control system shows good applicability and stability under the interference conditions of changing process conditions such as inlet air temperature,inlet air volume,atomization pressure,etc.Therefore,the fluidization state value feedback control system of fluidized bed granulation process based on near infrared spec-troscopy established in this paper has stability and reliability,and can provide strong technical sup-port for the intelligent manufacturing of fluidized bed granulation.

关键词

近红外光谱/流化床制粒/流化态值分析/反馈控制/自动控制

Key words

near infrared spectroscopy/fluidized bed granulation/fluidization state value analy-sis/feedback control/automatic control

分类

化学

引用本文复制引用

闫豪洁,陈杭,邱林钧,卢立明,瞿海斌..基于近红外光谱的流化床制粒过程流化态值反馈控制系统的构建与性能评估[J].分析测试学报,2025,44(6):1169-1175,7.

基金项目

国家重点研发计划(2023YFC3504501) (2023YFC3504501)

分析测试学报

OA北大核心

1004-4957

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