实用临床医药杂志2025，Vol.29Issue(9)：130-135,142,7.DOI:10.7619/jcmp.20245282
植物外泌体样纳米囊泡在骨骼疾病治疗中的研究进展
Research Progress of plant exosome-like nanovesicles in treatment of skeletal disorders
摘要
Abstract
Plant exosome-like nanovesicles(PELNs)are extracellular nanoparticles(30 to 300 nm in diameter)secreted by plant cells,characterized by a unique lipid-protein-nucleic acid compo-sition and functional attributes.These vesicles play pivotal roles in plant metabolism,immune de-fense,and the regulation of cellular physiological activities across species.This review systematically summarized recent research advances in PELNs,encompassing their biogenesis pathways,composi-tional analysis,extraction/isolation protocols,storage stability,identification methodologies,and ap-plications in skeletal system disorders.Critical challenges and future research directions in this field also discussed,providing valuable references for subsequent investigations.关键词
外泌体/细胞外囊泡/植物/骨质疏松/骨关节炎/靶向递送/生物相容性/提取Key words
exosome/extracellular vesicles/plant/osteoporosis/osteoarthritis/targeted de-livery/biocompatibility/extraction引用本文复制引用
吴楠,郭强强,郭华..植物外泌体样纳米囊泡在骨骼疾病治疗中的研究进展[J].实用临床医药杂志,2025,29(9):130-135,142,7.基金项目
陕西省西安市科技计划项目(22YXYJ0004) （22YXYJ0004）
