解放军医学杂志2025，Vol.50Issue(5)：505-512,8.DOI:10.11855/j.issn.0577-7402.0321.2025.0416
飞行人员血管源性脑白质高信号航空医学鉴定专家共识
Expert consensus on aeromedical identification of vasogenic white matter hyperintensities in aircrews
摘要
Abstract
White matter hyperintensities(WMH)are abnormal high-signal manifestations in white matter areas on magnetic resonance T2-weighted or fluid-attenuated inversion recovery(FLAIR)sequences,with vasogenic WMH being the most common.Its pathological mechanism is related to cerebrovascular lesions and can lead to multi-dimensional brain functional impairments in cognition,movement,and emotions.Due to their unique working conditions,aircrews are more prone to vasogenic WMH than the general population.Moreover,with the widespread use of magnetic resonance imaging in cranial disease screening for aircrews,the detection rate of vasogenic WMH in aircrews has significantly increased.However,to date,no national or academic organization has issued standardized aviation medical assessment criteria for vasogenic WMH in aircrews.Therefore,led by Xijing Hospital of Air Force Medical University and the Chinese PLA General Hospital,a multi-disciplinary expert panel involved in aviation medicine,neurology,radiology,psychology,and related fields was assembled to formulate this consensus.The document integrates evidence from a systematic review of PubMed,CNKI,Wanfang Data,and VIP databases,incorporates existing WMH guidelines,and synthesizes clinical expertise from Chinese specialists.The consensus outlines three key domains:target population,neuroimaging protocols for vasogenic WMH screening,and clinical assessment and aeromedical identification for aircrews with vasogenic WMH.The aim is to provide evidence-based support and expert recommendations for standardizing and improving the accuracy of aviation medical evaluations of vasogenic WMH in aircrews.关键词
飞行人员/血管源性脑白质高信号/头颅磁共振成像/医学鉴定Key words
aircrew/white matter hyperintensities/magnetic resonance imaging/medical assessment分类
临床医学引用本文复制引用
中国飞行人员血管源性脑白质高信号航空医学鉴定专家组,于生元,江文..飞行人员血管源性脑白质高信号航空医学鉴定专家共识[J].解放军医学杂志,2025,50(5):505-512,8.基金项目
This work was supported by the Military Medicine Promotion Program of Air Force Medical University(2020JSTS26) 空军军医大学军事医学提升计划项目(2020JSTS26) （2020JSTS26）
