结核与肺部疾病杂志2025，Vol.6Issue(3)：310-315,6.DOI:10.19983/j.issn.2096-8493.20250035
2005-2023年四川省凉山彝族自治州越西县肺结核流行趋势研究
Epidemiological trends of tuberculosis in Yuexi County,Liangshan Yi Autonomous Prefecture,Sichuan Province,2005-2023
摘要
Abstract
Objective:To examine the epidemiological trends of pulmonary tuberculosis in Yuexi County,Liangshan Yi Autonomous Prefecture,Sichuan Province,from 2005 to 2023,and to evaluate potential influencing factors including economic growth and transportation infrastructure development,with the aim of informing tuberculosis control strategies in resource-limited settings.Methods:Pulmonary tuberculosis case data from 2005 to 2023 were retrieved from the China Disease Control and Prevention Information System.Population and economic indicators were obtained from annual statistical yearbooks of Yuexi County.Descriptive epidemiological techniques were applied to assess incidence trends and their associations with macro-level socioeconomic variables.Results:Between 2005 and 2023,a total of 9856 pulmonary tuberculosis cases were reported in Yuexi County,corresponding to an average annual incidence rate of 151.66/100 000(9856/6 498 778).A statistically significant upward trend was observed over the study period(Z=11.519,P＜0.01),with an average annual growth rate of 1.77％.A geographic shift in reporting sources was noted:from 2005 to 2018,more than half of the cases were reported locally(e.g.,86.81％(375/432)in 2008),whereas since 2019,the majority of cases were reported by medical institutions outside the county(e.g.,60.16％(379/630)in 2023).Of these out-of-county reports,91.57％(3530/3855)were within Sichuan Province,predominantly from Xichang City(64.57％)and Chengdu City(18.13％).Marked spatial heterogeneity was observed across townships:Laji Township recorded the highest average incidence(211.58/100 000,193/91 219),whereas Zhongsuo Town had the lowest(79.07/100 000,311/393 300).Among all reported pulmonary tuberculosis cases,65.57％(6463/9856)were male,with an incidence rate of 170.70/100 000(6463/3 786 111),significantly higher than that observed in females(92.99/100 000,3393/3 648 931)(x2=867.890,P＜0.001).The highest burden was observed among individuals aged 18-60 years,who constituted 75.66％(7557/9856)of all cases,with an incidence of 185.09/100 000(7457/4 028 798).Farmers represented the predominant occupational group,accounting for 80.32％(7916/9856)of all cases.Joinpoint regression analysis indicated that the average annual percent change(AAPC)in tuberculosis incidence from 2005 to 2023 was 1.70％,with notable surges during 2005-2007(annual percent change(APC)=19.13％)and 2013-2016(APC=31.87％).During the same period,the per capita gross domestic product(GDP)in Yuexi County increased at an average annual rate of 9.06％,exhibiting a weak positive correlation with the tuberculosis incidence rate,described by the fitted curve:y=121+0.00242x.Conclusion:The burden of pulmonary tuberculosis in Yuexi County has continued to rise in parallel with economic development.Improvements in transportation infrastructure have facilitated cross-regional healthcare-seeking behavior,contributing to increased case detection outside the county.Young and middle-aged male farmers represent the primary high-risk population for tuberculosis in this setting.关键词
结核,肺/流行病学研究/小地区分析Key words
Tuberculosis,pulmonary/Epidemiologic studies/Small-area analysis分类
医药卫生引用本文复制引用
古勇,莫辉,陈红梅,卢波,易春梅,高志东,周晓凤,张泓泰..2005-2023年四川省凉山彝族自治州越西县肺结核流行趋势研究[J].结核与肺部疾病杂志,2025,6(3):310-315,6.基金项目
首都卫生发展科研专项(2024-2G-3017) Capital's Funds for Health Improvement and Research(2024-2G-3017) （2024-2G-3017）
