解放军医学杂志2025，Vol.50Issue(5)：523-530,8.DOI:10.11855/j.issn.0577-7402.1662.0831
内脏肥胖指数与夜尿症的关系:一项基于2007-2020年NHANES数据库的分析
Relationship between visceral adiposity index and nocturia:an analysis based on NHANES database from 2007 to 2020
摘要
Abstract
Objective To analyze the relationship between the visceral adiposity index(VAI)and nocturia in the US adult population.Methods A cross-sectional study was performed.Data from subjects aged≥20 years in the National Health and Nutrition Examination Survey(NHANES)database from 2007 to 2020 were collected,including waist circumference,triglyceride,body mass index(BMI),high-density lipoprotein,age,gender,race,poverty income ratio,education level,marital status,smoking,alcohol consumption,sleep disorders,depression,occupation,hypertension,diabetes,congestive heart failure,cancer,and nocturnal urination frequency.Weighted analysis,multivariate logistic regression,generalized additive model(GAM),and curve fitting were employed to evaluate the association between VAI and nocturia,adjusting for age,gender,race,poverty income ratio,education level,marital status,smoking,alcohol consumption,sleep disorders,depression,occupation,hypertension,diabetes,congestive heart failure,and cancer.Subgroup analyses were conducted based on age,gender,race,hypertension and diabetes to further evaluate the relationship between VAI and the risk of nocturia.Results A total of 29,196 American adults were included.All subjects were divided into 4 groups based on VAI quartiles:Q1 group(0.32≤VAI<1.01),Q2 group(1.01≤VAI<1.70),Q3 group(1.70≤VAI<2.95),and Q4 group(2.95≤VAI<13.59),with nocturia prevalence rates of 28.5%,31.4%,33.3%,and 34.9%,respectively.In subgroup analyses,the risk of nocturia significantly increased with higher VAI in the 20-40 age group,females and other Hispanics(OR=1.04,95%CI 1.01-1.08,P=0.006;OR=1.02,95%CI 1.00-1.04,P=0.035;OR=1.05,95%CI 1.01-1.09,P=0.026).GAM analysis results showed a nonlinear relationship between VAI and nocturia.Conclusion VAI is positively associated with the risk of nocturia,and may be an effective indicator for predicting the risk of nocturia occurrence.关键词
夜尿症/内脏肥胖指数/相关性/横断面研究Key words
nocturia/visceral obesity index/association/cross-sectional analysis分类
临床医学引用本文复制引用
罗振君,郝晓伟,王杰,黄帅,吴洋洋,吕凯凯,杨国荣,袁清..内脏肥胖指数与夜尿症的关系:一项基于2007-2020年NHANES数据库的分析[J].解放军医学杂志,2025,50(5):523-530,8.基金项目
This work was supported by the National Key Research and Development Program of China(2022YFC3602905),the Beijing Nova Program(20220284230),and the Youth Independent Innovation Science Fund of Chinese PLA General Hospital(22QNCZ016) 国家重点研发计划子课题(2022YFC3602905) （2022YFC3602905）
北京市科技新星计划交叉课题(20220284230) （20220284230）
解放军总医院青年自主创新科学基金(22QNCZ016) （22QNCZ016）
