实用临床医药杂志2025，Vol.29Issue(10)：146-148,3.DOI:10.7619/jcmp.20246081
误诊肝衰竭的不明原因横纹肌溶解所致的急性肾损伤1例
A case of acute kidney injury caused by unexplained rhabdomyolysis misdiagnosed as liver failure
摘要
Abstract
Rhabdomyolysis is a clinical syndrome characterized by damage to the integrity of skel-etal muscle cell membranes,massive release of intracellular contents(such as myoglobin,creatine ki-nase,and electrolytes)into the bloodstream,thereby triggering systemic pathophysiological responses.Its most common and severe complication is acute kidney injury,primarily resulting from the combined effects of myoglobin deposition in renal tubules and renal ischemia.Due to lack of specific early clini-cal manifestations,patients are often misdiagnosed or experience delayed treatment,which can lead to exacerbation of the condition and even life-threatening consequences.This article reports a case of a patient who presented with unexplained rhabdomyolysis at onset and subsequently developed acute kid-ney injury during the course of the disease.A systematic analysis and discussion of the potential etiolo-gy are conducted based on the patient's clinical features and laboratory test results.关键词
横纹肌溶解/急性肾损伤/肌红蛋白尿/病因分析/临床综合征/肌酸激酶/诊断延迟/病理生理机制Key words
rhabdomyolysis/acute kidney injury/myoglobinuria/etiology analysis/clinical syndrome/creatine kinase/delayed diagnosis/pathophysiological mechanism分类
医药卫生引用本文复制引用
彭蓝芬,占伯林,杨雯敏,杨渊,王严,孙嘉玲,周小舟..误诊肝衰竭的不明原因横纹肌溶解所致的急性肾损伤1例[J].实用临床医药杂志,2025,29(10):146-148,3.基金项目
国家自然科学基金项目(82374531,82205209) （82374531,82205209）
广东省深圳市科创委项目(JCYJ20210324120405015) （JCYJ20210324120405015）
