西南医科大学学报2025，Vol.48Issue(3)：275-280,6.DOI:10.3969/j.issn.2096-3351.2025.03.008
颈椎前路减压融合术应用3D cage与PEEK cage治疗单节段颈椎退行性疾病的疗效比较
Comparison of the Efficacy of Anterior Cervical Discectomy and Fusion Using 3D-Pinted ACT Titanium Cage Versus PEEK Cage for Single-Level Cervical Degenerative Disease
摘要
Abstract
Objective The purpose of this study is to compare the clinical efficacy of anterior cervical discectomy and fusion(ACDF)using a 3D-printed titanium trabecular interbody fusion cage(3D cage)and a polyether ether ketone(PEEK)interbody fusion cage in the treatment of single-level cervical degenerative diseases.Methods Retrospective analysis of 117 patients who under-went single-segment ACDF surgery in the Department of Orthopaedics,Affiliated Hospital of Chengdu University of Traditional Chi-nese Medicine,between December 2019 and December 2022,with n=57 in the study group(3D cage)and n=60 in the control group(PEEK cage).Baseline data,perioperative indices(operative time,bleeding,length of hospital stay),preoperative and postop-erative time at each time(3 months,1 year,and 2 years)Japanese Orthopaedic Association Scores(JOA),Neck Disability Index(NDI),and the imaging parameters of C2-7cobb angle,C2-7 sagittal vertical axis(cSVA),Disc Height(DH).Results There was no difference in intraoperative bleeding and length of hospital stay between the two groups,and the operative time in the study group was less than that in the control group(t=-3.481,P<0.001).JOA and NDI tended to optimise over time in both groups(FJOA=1386.234,PJOA<0.01,FNDI=1500.343,PNDI<0.001),and were better than preoperative up to 2 years postoperatively.There was an interaction between time and cage type for the C2-7cobb angle(F=3.523,P=0.014),the C2-7cobb angle was greater than preopera-tive in both groups in the postoperative period and at 3 months postoperatively,and in the postoperative period it was greater in the study group than in the control group.There was a trend in cSVA over time in both groups(F=70.153,P<0.001),and cSVA was less than preoperative in the postoperative period and at 3 months postoperatively.There was a trend in DH over time in both groups(F=109.004,P<0.001),and DH was higher in the postoperative period to the last follow-up than in the preoperative period.The fusion rate was greater in the study group than in the control group at 3 months postoperatively(χ2=4.308,P=0.038),and there was no difference in the fusion rate between the two groups from 1 year postoperatively to the final follow-up(P>0.05).There was no dif-ference in the incidence of complications between the two groups(χ2=0.052,P=0.820),and no serious complications requiring revi-sion occurred in either group.Conclusion The 3D cage significantly reduced operative time and facilitated early fusion at 3 months postoperatively,but there was no significant difference in clinical efficacy and complication rates between the two fusion devices at the 2-year follow-up period.关键词
3D打印/椎间融合器/颈椎前路减压融合术/颈椎病Key words
3D Printing/Interbody fusion Cage/Anterior cervical discectomy and Fusion/Cervical spondylopathy分类
基础医学引用本文复制引用
雷富豪,汪琨翔,杨涵翔,林可心,谢一舟,李统,余洋..颈椎前路减压融合术应用3D cage与PEEK cage治疗单节段颈椎退行性疾病的疗效比较[J].西南医科大学学报,2025,48(3):275-280,6.基金项目
四川省自然科学基金项目青年基金(25QNJJ1102) （25QNJJ1102）
