世界科学技术-中医药现代化2025，Vol.27Issue(5)：1219-1227,9.DOI:10.11842/wst.20240512002
基于ERPs技术探讨气郁质对大学生抑制控制功能的影响及其神经电生理机制
Exploring the Effect of Qi-Stagnation on Inhibitory Control Function and Its Neuroelectrophysiological Mechanism in College Students Based on ERP Technology
摘要
Abstract
Objective To investigate the effect of Qi stagnation on inhibitory control function and its neuroelectrophysiological mechanism in college students.Methods The population of peace and Qi depression was screened from college students through the scale of"Classification and Judgment Criteria of Traditional Chinese Medicine Constitution",and 35 subjects were included in each group.Combined with event-related potential technology,the two groups were collected to complete the Flanker paradigm behavioral indicators(accuracy,response time)and EEG data indicators(amplitude and latency of N2 and P3 components),and the behavioral differences and neuroelectrophysiological mechanisms between the two groups under the Flanker paradigm were explored.Results Compared with the flat group,the reaction time of the gas depression group was longer(P=0.07).Compared with the consistent dondition,the reaction time was longer under the inconsistent condition(P<0.001),and the accuracy rate was lower under the inconsistent condition significantly(P<0.001).Compared with the peaceful group,the N2 amplitude of the air depression group was higher(P<0.05).There was a statistically significant difference in the main effect of brain regions in the N2 latency period(P<0.001).Frontal lobe zero(Fz)in frontal region was greater than Frontal lobe central zero(FCz)in frontal region and greater than Central zero(Cz)in central region(P<0.05).There was a statistically significant difference in the main effect of brain region(P<0.001).FCz in the frontal central region was significantly greater than that in the frontal region Fz(P<0.001),and the difference was statistically significant in the central region Cz was significantly greater than that in the frontal region(P<0.001).The incubation period of P3 component was significantly smaller than that of inconsistent stimulation(P<0.001).Conclusion Qi stagnation has a negative effect on the inhibitory control function of college students,and the decline of conflict monitoring and control ability is one of the possible mechanisms.关键词
气郁质/抑制控制/Flanker范式/事件相关电位Key words
Qi-stagnation/Inhibition control/Flanker paradigm/Event-related potential分类
医药卫生引用本文复制引用
丁晓岐,刘永,侯俊林,赵紫薇,秦中朋,曹入元,詹向红..基于ERPs技术探讨气郁质对大学生抑制控制功能的影响及其神经电生理机制[J].世界科学技术-中医药现代化,2025,27(5):1219-1227,9.基金项目
国家自然科学基金委员会面上项目(81873208):肝失疏泄对正常人群和MCI患者认知功能衰退进程的影响及机制研究,负责人:詹向红 （81873208）
河南省双一流创建学科中医学科学研究专项(HSRP-DFCTCM-2023-1-02):负性情绪积累对aMCI患者执行功能的影响及疏肝法干预机制,负责人:詹向红 （HSRP-DFCTCM-2023-1-02）
河南省"双一流"创建学科中医学科学研究专项(HSRP-DFCTCM-2023-7-16):基于ERPs技术探讨疏肝解郁对阈下抑郁个体记忆维持的影响及机制,负责人:赵紫薇. （HSRP-DFCTCM-2023-7-16）
