上海预防医学2025，Vol.37Issue(4)：336-341,6.DOI:10.19428/j.cnki.sjpm.2025.24528
2013-2023年上海市奉贤区腹泻病监测病原谱
Pathogen spectrum of diarrheal disease surveillance in Fengxian District,Shanghai,2013‒2023
摘要
Abstract
[Objective]To investigate the pathogenic spectrum and epidemiological characteristics of diarrheal disease in Fengxian District of Shanghai,and to provide scientific basis for the prevention and control of diarrheal diseases.[Methods]Basic information of the initial adult cases visited diarrheal disease surveillance sentinel hospital in Fengxian District,Shanghai,was collected from August 2013 to 2023,and fecal samples were collected at 1∶5 sampling intervals to isolate and identify 5 kinds of diarrheagenic Escherichia coli(DEC),Salmonella(SAL),Vibrio parahaemolyticus,Campylobacter,Vibrio cholerae,Shigella and Yersinia enterocolitica(YE).Simultaneously,nucleic acid detection was performed for 3 kinds of rotavirus,2 kinds of norovirus,intestinal adenovirus,astrovirus and sapovirus.[Results]A total of 1 861 cases of newly diagnosed diarrheal disease were reported,with the peak in July to August.Additionally,704 surveillance samples were detected,with a total positive detection rate of 50.57%.The detection rates of bacterial,viral and mixed infection were 25.14%,21.02%and 4.40%,respectively.Among the pathogens detected,DEC accounted for the highest(17.61%,124/704),followed by norovirus(16.48%,116/704),rotavirus(6.39%,45/704),SAL(5.97%,42/704)and Campylobacter(3.84%,27/704).DEC detected were mainly enteroaggregative Escherichia coli and enterotoxigenic Escherichia coli,with no detection of Vibrio cholerae,Shigella and YE.The highest total pathogen detection rate was observed from June to September,and the detection peaks of norovirus were from March to June and from October to December,whereas that of DEC was from June to October.The detection rate of rotavirus peaked from January to February,but which was not detected between 2020‒2023.The SAL positive rate peak was in September,whereas that of Campylobacter was from July to September.[Conclusion]The main pathogens detected in Fengxian District from 2013‒2019 are DEC,norovirus,rotavirus,SAL and Campylobacter.Different pathogens have different detection peaks,with bacteria predominating in summer and viruses in winter and spring.Prevention and control measures should be carried out according to the epidemiological characteristics of different seasons.关键词
腹泻病/病原谱/监测/细菌/病毒Key words
diarrheal disease/pathogen spectrum/surveillance/bacteria/virus分类
医药卫生引用本文复制引用
刘梅花,庄源,谢晓红,赵宏伟,施媛,丁丽娟,胡屹,陶力新..2013-2023年上海市奉贤区腹泻病监测病原谱[J].上海预防医学,2025,37(4):336-341,6.基金项目
上海市加强公共卫生体系建设三年行动计划(2023-2025年)(GWⅥ-3) （2023-2025年）
